1.14.19.30: acyl-lipid (8-3)-desaturase

This is an abbreviated version!
For detailed information about acyl-lipid (8-3)-desaturase, go to the full flat file.

Reaction

Synonyms

acyl-lipid 5-desaturase, AL21, C20 DELTA5cis-desaturase, D5b, D5D, D5des, delta 5 desaturase, DELTA 5 fatty acid desaturase, delta-5 desaturase, DELTA-5-desaturase, DELTA5 desaturase, DELTA5 fatty acid desaturase, DELTA5-Des, DELTA5-desaturase, DELTA5-fatty acid desaturase, DELTA5-fatty-acid desaturase, DES5, desat7, FadA, FadB, FADS1, fads2b, FAT-4, fatty acid desaturase, PPDES5, PsD5Des

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.19 With oxidation of a pair of donors resulting in the reduction of O₂ to two molecules of water

                1.14.19.30 acyl-lipid (8-3)-desaturase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
3	Activating Compound
15	AA Sequence
5	Application
21	Cloned(Commentary)
26	Cofactor
205	Disease/ Diagnostics
4	Expression
11	General Information
25	IC50 Value
44	Inhibitors
2	Ki Value [mM]
2	KM Value [mM]
10	Localization
1	Molecular Weight [Da]
35	Natural Substrates/ Products (Substrates)
63	Organism
6	Pathway
1	pH Optimum
8	Reaction
46	Reference
38	Source Tissue
69	Substrates and Products (Substrate)
3	Subunits
81	Synonyms
1	Systematic Name

Systematic Name

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Systematic Name on EC 1.14.19.30 - acyl-lipid (8-3)-desaturase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

DELTA8 acyl-lipid,ferrocytochrome b5:oxygen oxidoreductase (5,6 cis-dehydrogenating)

The enzyme, which has been characterized from multiple organisms including the moss Physcomitrella patens, the marine microalga Rebecca salina, and the filamentous fungus Mortierella alpina, introduces a cis double bond at the 5-position in 20-carbon polyunsaturated fatty acids incorporated in a glycerolipid that contain a Delta8 double bond. The enzyme contains a cytochrome b5 domain that acts as the direct electron donor to the active site of the desaturase, and does not require an external cytochrome.