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1.14.19.30: acyl-lipid (8-3)-desaturase

This is an abbreviated version!
For detailed information about acyl-lipid (8-3)-desaturase, go to the full flat file.

Word Map on EC 1.14.19.30

Reaction

an (8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid]
+ 2 ferrocytochrome b5 +
O2
 + 2 H+ =
a (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid]
 + 2 ferricytochrome b5 + 2 H2O

Synonyms

acyl-lipid 5-desaturase, AL21, C20 DELTA5cis-desaturase, D5b, D5D, D5des, delta 5 desaturase, DELTA 5 fatty acid desaturase, delta-5 desaturase, DELTA-5-desaturase, DELTA5 desaturase, DELTA5 fatty acid desaturase, DELTA5-Des, DELTA5-desaturase, DELTA5-fatty acid desaturase, DELTA5-fatty-acid desaturase, DES5, desat7, FadA, FadB, FADS1, fads2b, FAT-4, fatty acid desaturase, PPDES5, PsD5Des

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.30 acyl-lipid (8-3)-desaturase

Inhibitors

Inhibitors on EC 1.14.19.30 - acyl-lipid (8-3)-desaturase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(+)-episesamin
-
specific inhibitor
(+)-sesamin
-
specific inhibitor
(+)-sesaminol
-
specific inhibitor
(+)-sesamolin
-
specific inhibitor
(-)-asarinin
-
non-competitive inhibitor
(-)-epiasarinin
-
non-competitive inhibitor
2-(2,2,3,3,3-pentafluoropropoxy)-3-[4-(2,2,2-trifluoroethoxy)phenyl]-5,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-4,6-dione
-
-
2-amino-5-chloro-N-(3-chlorophenyl)benzamide
-
-
2-amino-N-(3-chlorophenyl)-5-fluorobenzamide
-
-
2-amino-N-(3-chlorophenyl)benzamide
-
-
2-amino-N-(3-fluorophenyl)benzamide
-
-
2-amino-N-[3-(propan-2-yl)phenyl]benzamide
-
-
3,5-diphenyl-1,3-oxazolidin-2-one
3-[(4S,5S)-5-(4-fluorophenyl)-4-methyl-2-oxo-1,3-oxazolidin-3-yl]benzonitrile
4-isopentoxyaniline
-
-
5-bromo-N-(3-chlorophenyl)-1H-indazol-3-amine
-
-
5-chloro-N-(3-chlorophenyl)-1H-indazol-3-amine
-
-
5-[(4S,5S)-5-(4-fluorophenyl)-4-methyl-2-oxo-1,3-oxazolidin-3-yl]benzene-1,3-dicarbonitrile
CP-24879
the combined DELTA5 desaturase/DELTA6 desaturase inhibitor significantly reduces intracellular lipid accumulation and inflammatory injury in hepatocytes
dibenzoazepine
-
-
N-(3-chlorophenyl)-1H-indazol-3-amine
-
-
N-(3-chlorophenyl)-2,3-dihydro-1H-inden-1-amine
-
-
N-(3-chlorophenyl)-2-hydroxy-5-methoxybenzamide
-
-
N-(3-chlorophenyl)-2-hydroxybenzamide
-
-
N-(3-chlorophenyl)-5-(trifluoromethoxy)-1H-indazol-3-amine
-
-
N-(3-chlorophenyl)-5-(trifluoromethyl)-1H-indazol-3-amine
-
-
N-(3-chlorophenyl)-5-ethoxy-2-hydroxybenzamide
-
-
N-(3-chlorophenyl)-5-fluoro-1H-indazol-3-amine
-
-
N-(3-chlorophenyl)-5-methoxy-1H-indazol-3-amine
-
-
N-(3-chlorophenyl)-5-methyl-1H-indazol-3-amine
-
-
N-(3-chlorophenyl)furo[3,2-c]pyridin-4-amine
-
-
N-(3-chlorophenyl)naphthalen-1-amine
-
-
N-(3-chlorophenyl)quinazolin-4-amine
-
-
N-(3-chlorophenyl)quinolin-4-amine
-
-
N-(3-chlorophenyl)thieno[2,3-d]pyrimidin-4-amine
-
-
N-(3-chlorophenyl)thieno[3,2-d]pyrimidin-4-amine
-
-
N-(3-fluorophenyl)-1H-indazol-3-amine
-
-
sesamin
-
-