1.14.19.25: acyl-lipid omega-3 desaturase (cytochrome b5)
This is an abbreviated version!
For detailed information about acyl-lipid omega-3 desaturase (cytochrome b5), go to the full flat file.
Word Map on EC 1.14.19.25
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1.14.19.25
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linolenic
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polyunsaturated
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desaturases
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pufas
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alpha-linolenic
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desaturation
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flax
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usitatissimum
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linum
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trienoic
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omega-6
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stearoyl-acp
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medicine
- 1.14.19.25
-
linolenic
-
polyunsaturated
-
desaturases
-
pufas
-
alpha-linolenic
-
desaturation
- flax
- usitatissimum
-
linum
-
trienoic
-
omega-6
- stearoyl-acp
- medicine
Reaction
+ 2 ferrocytochrome b5 + + 2 H+ = + 2 ferricytochrome b5 + 2 H2O
Synonyms
BjFad3, DELTA15 desaturase, endoplasmic reticulum-type omega-3 fatty acid desaturase, ER-localized omega-3 FA desaturase, ER-type desaturase, ER-type omega-3 fatty acid desaturase, FAD3, FAD3-1, FAD3-2, FAD3A, FAD3B, FAD3C, fatty acid desaturase 3, LeFAD3, maw3, msdd17, omega-3 desaturase, omega-3 FA desaturase, omega-3 FAD, omega-3 fatty acid desaturase, omega3-desaturase, PfrFAD3, sdd17
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General Information
General Information on EC 1.14.19.25 - acyl-lipid omega-3 desaturase (cytochrome b5)
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malfunction
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accumulation of linoleoyl (18:2) groups at the expense of linolenoyl groups (18:3) is the only substantial difference in membrane lipid biosynthesis in leaves and roots of fad3-2 plants relative to wild type
metabolism
physiological function
additional information
regulation of the enzyme through synergistic and antagonistic hormonal interactions, overview
metabolism
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regulation of the enzyme through synergistic and antagonistic hormonal interactions, overview
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OMEGA-3 fatty acid desaturase converts exogenous arachidonic acid, an OMEGA-6 PUFA, into eicosapentaenoic acid (EPA). Gene sdd17 from EPA-rich fungus is expressed at high levels and increases OMEGA-3 fatty acid concentrations in mammalian cells
physiological function
the omega-3 FAD gene expression product and its enzymatic product C18:3n3 are crucial to the microalgae cell system
physiological function
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tomato endoplasmic reticulum-type omega-3 fatty acid desaturase functions in early seedling tolerance to salinity stress
physiological function
Chlorella vulgaris UMT-M1
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the omega-3 FAD gene expression product and its enzymatic product C18:3n3 are crucial to the microalgae cell system
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fatty acid profile of wild-type and fad3 mutant roots in response to several plant hormones, overview
additional information
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fatty acid profile of wild-type and fad3 mutant roots in response to several plant hormones, overview
additional information
the enzyme contains the conserved His box of plant omega-3 FA desaturase. One amino acid residue, Asn or Ser, is different at 61 position of PfrFAD3-1 and PfrFAD3-2, respectively. Both PfrFAD3-1 and -2 have the function of omega-3 FA desaturases
additional information
the enzyme contains the conserved His box of plant omega-3 FA desaturase. One amino acid residue, Asn or Ser, is different at 61 position of PfrFAD3-1 and PfrFAD3-2, respectively. Both PfrFAD3-1 and -2 have the function of omega-3 FA desaturases
additional information
-
fatty acid profile of wild-type and fad3 mutant roots in response to several plant hormones, overview
-