1.14.18.5: sphingolipid C4-monooxygenase

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For detailed information about sphingolipid C4-monooxygenase, go to the full flat file.

Word Map on EC 1.14.18.5

1.14.18.5

sphingolipids

sphingoid

phytosphingosine

phytoceramide

oxygen-dependent

inositolphosphorylceramide

c4-hydroxylation

nidulans

dihydrosphingosine

Reaction

+ 2 ferrocytochrome b5 +

+ 2 H+ =

+ 2 ferricytochrome b5 +

Synonyms

bifunctional sphingolipid D4-desaturase/C4-hydroxylase, DES2, DHS hydroxylase, dihydroceramide hydrolase, dihydroceramide hydroxylase, EC 1.14.13.169, LmjF_26_1670, SBH1, SBH2, SC4H, sphinganine C4-hydroxylase, sphinganine C4-monooxygenase, sphingolipid C4-hydroxylase, sphingolipid delta(4)-desaturase/C4-monooxygenase, sphingolipid hydroxylase, SUR2, Sur2p, SYR2, Syr2p

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor

1.14.18.5 sphingolipid C4-monooxygenase

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Results	in table
30	AA Sequence
6	Cloned(Commentary)
2	Expression
9	General Information
3	KM Value [mM]
3	Localization
1	Metals/Ions
2	Molecular Weight [Da]
12	Organism
4	Pathway
19	Protein Variants
1	Reaction
12	Reference
5	Source Tissue
19	Substrates and Products (Substrate)
2	Subunits
37	Synonyms
1	Systematic Name

Organism

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Organism on EC 1.14.18.5 - sphingolipid C4-monooxygenase

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UniProt

UniProt

Leishmania major has four genes occurring in tandem arrays, with at least three of them encoding active bifunctional enzymes

734653

G3FCJ2

UniProt

Mus musculus

bifunctional sphingolipid delta(4)-desaturase/C4-monooxygenase

734141

Q8R2F2

UniProt

Saccharomyces cerevisiae

2 entries

Saccharomyces cerevisiae W303C

719795

Wickerhamomyces ciferrii

formerly Pichia ciferrii

UniProt