1.14.18.1: tyrosinase This is an abbreviated version! For detailed information about tyrosinase, go to the full flat file .
Reaction
2 L-dopa
+
O2 =
2 dopaquinone
+
2 H2O
Synonyms AbPPO1, AbPPO4, AbTYR, aurone synthase, catalase-phenol oxidase, catechol oxidase, catecholase, CATPO, chlorogenic acid oxidase, chlorogenic oxidase, cresolase, cresolase/monophenolase, CsPPO, CZA14Tyr, deoxy-tyrosinase, dihydroxy-L-phenylalanine:oxygen oxidoreductase, Diphenol oxidase, diphenolase, dopa oxidase, EC 1.10.3.1, EC 1.14.17.2, Hc-derived phenoloxidase, Hc-phenoloxidase, HcPO, HdPO, hemocyanin-derived phenoloxidase, jrPPO1, jrTYR, L-DOPA monophenolase, L-DOPA oxidase, L-DOPA:oxygen oxidoreductase, L-tyrosine hydroxylase, MdPPO1, melC2, MelC2 tyrosinase, met-tyrosinase, monophenol dihydroxyphenylalanine:oxygen oxidoreductase, monophenol monooxidase, monophenol monooxygenase, monophenol monoxygenase, monophenol oxidase, monophenol oxygen oxidoreductase, monophenol, 3,4-dihydroxy L-phenylalanine (L-DOPA):oxygen oxidoreductase, monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase, monophenol, dihydroxy-L-phenylalanine:oxygen oxidoreductase, monophenol, dihydroxyphenylalanine:oxygen oxidoreductase, monophenol, L-Dopa: oxidoreductase, monophenol, L-DOPA: oxygen oxidoreductase, monophenol, o-diphenol: oxygen oxidoreductase, monophenol, o-diphenol:O2 oxidoreductase, monophenol, o-diphenol:oxygen oxido-reductase, monophenol, o-diphenol:oxygen oxidoreductase, monophenol, polyphenol oxidase, monophenol: dioxygen oxidoreductases, hydroxylating, monophenolase, monphenol mono-oxygenase, More, mTyr, murine tyrosinase, mushroom tyrosinase, mushroom tyrosine, N-acetyl-6-hydroxytryptophan oxidase, o-diphenol oxidase, o-diphenol oxidoreductase, o-diphenol oxygen oxidoreductase, o-diphenol: O2 oxidoreductase, o-diphenol: oxidoreductase, o-diphenol:O2 oxidoreductase, o-diphenol:oxygen oxidoreductase, o-diphenolase, OCA1, Orf13, oxygen oxidoreductase, phenol oxidase, phenol oxidases, phenolase, phenoloxidase, PO, polyaromatic oxidase, polyphenol oxidase, polyphenol oxidase 3, polyphenol oxidase 4, polyphenol oxidase B, polyphenolase, polyphenoloxidase, PotPPO, PPO, PPO 3, PPO B, PPO1, PPO2, PPO3, pro-PO III, prophenoloxidase III, pyrocatechol oxidase, SPRTyr, ST94, ST94t, tryosinase, tryrosinase, TY, tyr, TYR1, TYR2, tyrA, TyrBm, tyrosinase, tyrosinase 2, tyrosinase 4, tyrosinase diphenolase, tyrosine-dopa oxidase
ECTree
Synonyms
Synonyms on EC 1.14.18.1 - tyrosinase
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chlorogenic acid oxidase
-
-
-
-
chlorogenic oxidase
-
-
-
-
cresolase/monophenolase
-
-
dihydroxy-L-phenylalanine:oxygen oxidoreductase
-
-
EC 1.10.3.1
-
-
related
-
EC 1.14.17.2
-
-
formerly
-
Hc-derived phenoloxidase
-
-
hemocyanin-derived phenoloxidase
-
-
L-DOPA:oxygen oxidoreductase
-
-
L-tyrosine hydroxylase
-
-
monophenol dihydroxyphenylalanine:oxygen oxidoreductase
-
-
-
-
monophenol monooxidase
-
-
-
-
monophenol monoxygenase
-
-
monophenol oxidase
-
-
-
-
monophenol oxygen oxidoreductase
-
-
monophenol, 3,4-dihydroxy L-phenylalanine (L-DOPA):oxygen oxidoreductase
-
monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase
-
-
-
-
monophenol, dihydroxy-L-phenylalanine:oxygen oxidoreductase
-
-
monophenol, dihydroxyphenylalanine:oxygen oxidoreductase
-
copper binding metalloenzyme
monophenol, L-Dopa: oxidoreductase
-
monophenol, L-DOPA: oxygen oxidoreductase
monophenol, o-diphenol: oxygen oxidoreductase
monophenol, o-diphenol:O2 oxidoreductase
-
-
monophenol, o-diphenol:oxygen oxido-reductase
-
monophenol, o-diphenol:oxygen oxidoreductase
monophenol, polyphenol oxidase
-
-
monophenol: dioxygen oxidoreductases, hydroxylating
-
-
monphenol mono-oxygenase
-
-
murine tyrosinase
-
from cultured B16 cells
N-acetyl-6-hydroxytryptophan oxidase
-
-
-
-
o-diphenol oxidoreductase
-
-
-
-
o-diphenol oxygen oxidoreductase
-
-
o-diphenol: O2 oxidoreductase
-
-
o-diphenol: oxidoreductase
-
-
o-diphenol:O2 oxidoreductase
-
-
-
-
o-diphenol:oxygen oxidoreductase
-
-
-
-
oxygen oxidoreductase
-
-
polyaromatic oxidase
-
-
-
-
polyphenol oxidase 4
UniProt
pyrocatechol oxidase
-
-
-
-
ST94t
the tyrosinase activity of ST94 is enhanced by proteolysis with trypsin to form a protein, termed ST94t
tyrosinase diphenolase
-
-
tyrosine-dopa oxidase
-
-
-
-
catalase-phenol oxidase
-
bifunctional enzyme
catalase-phenol oxidase
-
bifunctional enzyme, its major activity is the catalase-mediated decomposition of hydrogen peroxide, but it also catalyzes peroxide-independent phenol oxidation
catechol oxidase
-
-
-
-
catecholase
-
-
-
-
cresolase
-
-
-
-
CZA14Tyr
-
-
Diphenol oxidase
-
-
-
-
diphenolase
-
dopa oxidase
-
-
-
-
dopa oxidase
-
DOPA oxidase activity of murine tyrosinase
melC2
-
MelC2 tyrosinase
-
-
monophenol monooxygenase
-
-
monophenol monooxygenase
-
-
monophenol monooxygenase
-
-
monophenol monooxygenase
-
-
monophenol monooxygenase
-
-
monophenol monooxygenase
-
-
monophenol monooxygenase
-
monophenol monooxygenase
-
-
monophenol, L-DOPA: oxygen oxidoreductase
-
-
monophenol, L-DOPA: oxygen oxidoreductase
-
monophenol, o-diphenol: oxygen oxidoreductase
-
monophenol, o-diphenol: oxygen oxidoreductase
-
-
monophenol, o-diphenol: oxygen oxidoreductase
-
-
monophenol, o-diphenol: oxygen oxidoreductase
-
monophenol, o-diphenol:oxygen oxidoreductase
-
-
monophenol, o-diphenol:oxygen oxidoreductase
-
monophenol, o-diphenol:oxygen oxidoreductase
-
-
monophenol, o-diphenol:oxygen oxidoreductase
-
monophenol, o-diphenol:oxygen oxidoreductase
-
-
monophenol, o-diphenol:oxygen oxidoreductase
-
-
monophenolase
-
-
-
-
mushroom tyrosinase
-
-
744014 , 744462 , 744483 , 744486 , 744488 , 744490 , 744491 , 744495 , 744511 , 744669 , 744671 , 744676 , 744819 , 744844 , 745095 , 745129 , 745130 , 745131 , 745133 , 745138 , 745139 , 745406 , 746193 , 746222 , 746346 , 746498
o-diphenol oxidase
-
-
-
-
o-diphenol oxidase
Helix vulgaris
-
-
o-diphenolase
-
-
-
-
phenol oxidase
-
-
-
-
phenolase
-
-
-
-
phenoloxidase
-
-
polyphenol oxidase
-
-
-
-
polyphenol oxidase
-
-
685018 , 685461 , 685515 , 685530 , 685671 , 685753 , 687154 , 688026 , 688039 , 689064 , 689440 , 696463 , 696757 , 697303 , 698040 , 698391 , 712597 , 726870
polyphenol oxidase
-
catalyzes both the hydroxylation of monophenols to diphenols and the oxidation of o-diphenols to o-quinones
polyphenol oxidase
-
a binuclear copper containing metalloprotein
polyphenol oxidase
-
responsible for browning reaction in demaged plant tissues and fruits
polyphenol oxidase
-
acts like cresolase and catecholase
polyphenol oxidase
-
EC1.14.18.1, EC1.10.3.1
polyphenol oxidase
Festuca sp.
-
-
polyphenol oxidase
Lolium sp.
-
-
polyphenoloxidase
-
-
polyphenoloxidase
Coffea guarini
-
-
PPO
-
-
PPO
-
enzyme catalyses two distinct reactions: the o-hydroxylation of monophenols to o-diphenols (acts like cresolase) (E.C. 1.14.18.1) and the oxidation of o-diphenols to o-quinones (acts like catecholase) (E.C. 1.10.3.2)
PPO1
-
-
PPO2
-
SPRTyr
-
-
tyr
-
-
TYR2
isozyme
tyrA
has both monophenol oxidase and diphenol oxidase activity
tyrA
has both monophenol oxidase and diphenol oxidase activity
-
tyrosinase
-
-
-
-
tyrosinase
-
-
672488 , 672593 , 673001 , 674114 , 675458 , 676133 , 684129 , 685018 , 685452 , 685458 , 685461 , 685462 , 685515 , 685530 , 685604 , 685609 , 685668 , 685671 , 685753 , 686065 , 686532 , 687260 , 688030 , 688039 , 688041 , 688054 , 688064 , 688305 , 688592 , 689064 , 689106 , 689118 , 689278 , 689383 , 689413 , 689436 , 689439 , 689440 , 689441 , 689442 , 689702 , 695931 , 696463 , 696563 , 696650 , 696667 , 696757 , 696758 , 696844 , 697303 , 697659 , 697741 , 697742 , 697744 , 698040 , 698391 , 698427 , 698442 , 699039 , 699195 , 699239 , 699403 , 699640 , 700322 , 700323 , 700853 , 710912 , 711435 , 711457 , 711476 , 712217 , 712534 , 712597 , 713205
tyrosinase
-
a real tyrosinase because it shows both diphenolase and monophenolase activities
tyrosinase
-
catalyzes two distinct reactions of melanin biosynthesis: the o-hydroxylation of the amino acid L-tyrosine to L-DOPA and subsequently the oxidation of L-DOPA to the corresponding o-dopaquinone
tyrosinase
-
copper-containing monooxygenase
tyrosinase
-
rate-limiting enzyme in melanin synthesis
tyrosinase
-
this enzyme is able to catalyse two different reactions: the hydroxylation of monophenols to o-diphenols (monophenolase or cresolase activity, EC 1.14.18.1), and the oxidation of o-diphenols to o-quinones (diphenolase or catechol oxidase activity, EC 1.10.3.1)
tyrosinase
Helix vulgaris
-
-
tyrosinase
-
plays a core role in melanogenesis
tyrosinase
-
this enzyme is able to catalyse two different reactions: the hydroxylation of monophenols to o-diphenols (monophenolase or cresolase activity, EC 1.14.18.1), and the oxidation of o-diphenols to o-quinones (diphenolase or catechol oxidase activity, EC 1.10.3.1)
tyrosinase
-
this enzyme is able to catalyse two different reactions: the hydroxylation of monophenols to o-diphenols (monophenolase or cresolase activity, EC 1.14.18.1), and the oxidation of o-diphenols to o-quinones (diphenolase or catechol oxidase activity, EC 1.10.3.1)
tyrosinase
-
binuclear copper enzyme
tyrosinase
-
this enzyme is able to catalyse two different reactions: the hydroxylation of monophenols to o-diphenols (monophenolase or cresolase activity, EC 1.14.18.1), and the oxidation of o-diphenols to o-quinones (diphenolase or catechol oxidase activity, EC 1.10.3.1)
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
cf. EC 1.21.3.6
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
Coffea guarini
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1
additional information
-
cf. EC 1.10.3.1