1.14.16.2: tyrosine 3-monooxygenase
This is an abbreviated version!
For detailed information about tyrosine 3-monooxygenase, go to the full flat file.
Word Map on EC 1.14.16.2
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1.14.16.2
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dopamine
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dopaminergic
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parkinsonism
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nigra
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striatum
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catecholamine
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substantia
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nerve
-
ventral
-
fiber
-
sympathetic
-
innervation
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adrenal
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noradrenergic
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neurotransmitter
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6-hydroxydopamine
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ganglia
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th-positive
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catecholaminergic
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neuropeptide
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norepinephrine
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nigrostriatal
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midbrain
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monoamine
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neurotrophic
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compacta
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coeruleus
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hypothalamus
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tegmental
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mesencephalic
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1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
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l-dopa
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6-ohda
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neurochemical
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accumbens
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noradrenaline
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rostrally
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dopac
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apomorphine
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perikarya
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intrastriatal
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beta-hydroxylase
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mptp-induced
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varicosity
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ventrolateral
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dopamine-beta-hydroxylase
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preoptic
-
npy
-
phenylethanolamine
-
analysis
-
diagnostics
-
homovanillic
-
synthesis
- 1.14.16.2
- dopamine
-
dopaminergic
- parkinsonism
- nigra
- striatum
- catecholamine
-
substantia
- nerve
-
ventral
- fiber
-
sympathetic
-
innervation
- adrenal
-
noradrenergic
-
neurotransmitter
- 6-hydroxydopamine
- ganglia
-
th-positive
-
catecholaminergic
-
neuropeptide
- norepinephrine
-
nigrostriatal
- midbrain
-
monoamine
-
neurotrophic
- compacta
- coeruleus
- hypothalamus
- tegmental
-
mesencephalic
- 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
- l-dopa
-
6-ohda
-
neurochemical
- accumbens
- noradrenaline
-
rostrally
-
dopac
- apomorphine
- perikarya
-
intrastriatal
- beta-hydroxylase
-
mptp-induced
-
varicosity
-
ventrolateral
- dopamine-beta-hydroxylase
-
preoptic
- npy
- phenylethanolamine
- analysis
- diagnostics
-
homovanillic
- synthesis
Reaction
Synonyms
CAT-2, DTH1, DTH2, hTH2, L-tyrosine hydroxylase, monophenol monooxygenase, oxygenase, tyrosine 3-mono-, TH, TH1, TH2, TyrH, tyrosinase, tyrosine 3-hydroxylase, tyrosine 3-monooxygenase, tyrosine hydroxylase, tyrosine hydroxylase type 1, tyrosine-3-mono-oxygenase, tyrosine-3-monooxygenase
ECTree
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Specific Activity
Specific Activity on EC 1.14.16.2 - tyrosine 3-monooxygenase
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0.00045
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about, MN9D cells induced by forskolin or 8-(4-chlorophenylthio)adenosine 3',5'-cyclic monophosphate
0.00368
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activity of tyrosine hydroxylase, control level without treatment of L-DOPA in PC-12 cells
0.2
additional information
additional information
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tyrosine hydroxylase expression and activity in wild-type MN9D cells, in alpha-synuclein-deficient MN9D cells, and in MN9D cells transfected with alpha-synuclein, overview
additional information
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activity of immobilized enzyme under different conditions in bioreactors
additional information
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217% activity compared to control level, treatment with 0.02 mM L-DOPA in PC-12 cells at 6 h time point
additional information
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232% activity compared to control level, treatment with 0.1 mM L-DOPA in PC-12 cells at 6 h time point
additional information
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272% activity compared to control level, treatment with 0.02 mM L-DOPA in PC-12 cells at 6 h time point
additional information
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55.2% activity compared to control level, treatment with 0.2 mM L-DOPA in PC-12 cells at 48 h time point
additional information
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62.6% activity compared to control level, treatment with 0.2 mM L-DOPA in PC-12 cells at 1 h time point
additional information
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68.2% activity compared to control level, treatment with 0.1 mM L-DOPA in PC-12 cells at 1 h time point
additional information
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82.2% activity of tyrosine hydroxylase compared to control level, treatment with 0.02 mM L-DOPA in PC-12 cells at 1 h time point
additional information
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82.3% activity compared to control level, treatment with 0.1 mM L-DOPA in PC-12 cells at 48 h time point
additional information
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activity returns to the control level between 24-48 h after treatment with 0.02 mM L-DOPA.