Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.15.22: vitamin D 1,25-hydroxylase

This is an abbreviated version!
For detailed information about vitamin D 1,25-hydroxylase, go to the full flat file.

Word Map on EC 1.14.15.22

Reaction

calcidiol
+ 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ +
O2
=
calcitriol
+ 2 oxidized ferredoxin [iron-sulfur] cluster +
H2O

Synonyms

CYP105A1, cytochrome P450SU-1, Streptomyces griseolus cytochrome P450SU-1, vitamin D3 dihydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.15.22 vitamin D 1,25-hydroxylase

Turnover Number

Turnover Number on EC 1.14.15.22 - vitamin D 1,25-hydroxylase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0009
1alpha,25-dihydroxyvitamin D3
26-hydroxylation, mutant R73V/R84A, pH not specified in the publication, temperature not specified in the publication
0.035
1alpha-hydroxyvitamin D3
25-hydroxylation, mutant R73V/R84A, pH not specified in the publication, temperature not specified in the publication
0.0023
25-hydroxyvitamin D3
1alpha-hydroxylation, mutant R73V/R84A, pH not specified in the publication, temperature not specified in the publication
0.0023
vitamin D3
25-hydroxylation, mutant R73V/R84A, pH not specified in the publication, temperature not specified in the publication