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1.14.15.13: pulcherriminic acid synthase

This is an abbreviated version!
For detailed information about pulcherriminic acid synthase, go to the full flat file.

Reaction

cyclo(L-leucyl-L-leucyl)
+ 6 reduced ferredoxin + 3 O2 =
pulcherriminic acid
+ 6 oxidized ferredoxin + 4 H2O + 6 H+

Synonyms

cyclo-L-leucyl-L-leucyl dipeptide oxidase, CYP134A1, CypX

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.15.13 pulcherriminic acid synthase

Systematic Name

Systematic Name on EC 1.14.15.13 - pulcherriminic acid synthase

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SYSTEMATIC NAME
IUBMB Comments
cyclo(L-leucyl-L-leucyl),reduced-ferredoxin:oxygen oxidoreductase (N-hydroxylating,aromatizing)
A heme-thiolate (P-450) enzyme from the bacterium Bacillus subtilis. The order of events during the overall reaction is unknown. Pulcherrimic acid spontaneously forms an iron chelate with Fe(3+) to form the red pigment pulcherrimin [2].