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1.14.14.26: 24-hydroxycholesterol 7alpha-hydroxylase

This is an abbreviated version!
For detailed information about 24-hydroxycholesterol 7alpha-hydroxylase, go to the full flat file.

Word Map on EC 1.14.14.26

Reaction

(24S)-cholest-5-ene-3beta,24-diol
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(24S)-cholest-5-ene-3beta,7alpha,24-triol
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

24-hydroxycholesterol 7alpha-monooxygenase, Cyp39a1, CYP39A1 oxysterol 7alpha-hydroxylase, EC 1.14.13.99, oxysterol 7alpha-hydroxylase CYP39A1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.26 24-hydroxycholesterol 7alpha-hydroxylase

Sequence

Sequence on EC 1.14.14.26 - 24-hydroxycholesterol 7alpha-hydroxylase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CP7A1_HUMAN
504
1
57661
Swiss-Prot
Secretory Pathway (Reliability: 1)
CP7A1_MOUSE
503
1
57262
Swiss-Prot
Secretory Pathway (Reliability: 1)
CP7A1_PIG
501
1
56846
Swiss-Prot
Secretory Pathway (Reliability: 1)
CP7A1_RABIT
501
1
58090
Swiss-Prot
Secretory Pathway (Reliability: 1)
CP7A1_RAT
503
1
56883
Swiss-Prot
Secretory Pathway (Reliability: 1)
CP7B1_HUMAN
506
2
58256
Swiss-Prot
Secretory Pathway (Reliability: 4)
CP7B1_MOUSE
507
3
58470
Swiss-Prot
Secretory Pathway (Reliability: 2)
CP39A_HUMAN
469
2
54116
Swiss-Prot
Secretory Pathway (Reliability: 1)
CP39A_MOUSE
470
0
53575
Swiss-Prot
Secretory Pathway (Reliability: 1)
M2Y4F8_GALSU
473
1
53969
TrEMBL
Secretory Pathway (Reliability: 1)
A1A611_XENLA
479
1
54584
TrEMBL
Secretory Pathway (Reliability: 2)
A0A8B6DLP9_MYTGA
343
1
39917
TrEMBL
other Location (Reliability: 3)
A0A0B7FGK5_THACB
Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14)
509
0
57061
TrEMBL
other Location (Reliability: 3)
A0A6J8DQC3_MYTCO
425
1
49561
TrEMBL
other Location (Reliability: 4)
A0A061IKF2_CRIGR
471
1
54195
TrEMBL
Secretory Pathway (Reliability: 1)
A0A8B6ESD8_MYTGA
285
1
32850
TrEMBL
Secretory Pathway (Reliability: 2)
A0A8M1N7I9_DANRE
464
2
52864
TrEMBL
Secretory Pathway (Reliability: 1)
A0A6J8DPF0_MYTCO
447
1
52094
TrEMBL
other Location (Reliability: 4)