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1.14.14.14: aromatase

This is an abbreviated version!
For detailed information about aromatase, go to the full flat file.

Word Map on EC 1.14.14.14

Reaction

19-hydroxyandrost-4-ene-3,17-dione
+
O2
+
[reduced NADPH-hemoprotein reductase]
=
19-oxo-androst-4-ene-3,17-dione
+ 2 H2O +
[oxidized NADPH-hemoprotein reductase]

Synonyms

AROM, Cyp19a, CYP19A1, Cyp19a1a, Cyp19a1b, Cyp19A3, cytochrome P450 aromatase, P450arom

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.14 aromatase

KM Value

KM Value on EC 1.14.14.14 - aromatase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.058
16alpha-hydroxytestosterone
-
pH 7.2, 37°C
0.00006 - 0.0002
androst-4-ene-3,17-dione
0.00021
testosterone
-
pH 7.2, 37°C
additional information
androst-4-ene-3,17-dione