1.14.13.76: taxane 10beta-hydroxylase

This is an abbreviated version, for detailed information about taxane 10beta-hydroxylase, go to the full flat file.

Reaction

taxa-4(20),11-dien-5alpha-yl acetate
+
NADPH
 +
H+
 +
O2
=
10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate
 +
NADP+
 +
H2O

Synonyms

5-alpha-taxadienol-10-beta-hydroxylase, cytochrome P450 reductase, NADPH:cytochrome P450 reductase, oxygenase, taxane 10beta-mono-, taxa-4(20),11-dien-5alpha-yl acetate 10beta-hydroxylase, taxadien-5alpha-yl-acetate 10beta-hydroxylase, taxane 10beta-hydroxylase, taxane 10beta-monooxygenase, taxoid 10beta-hydroxylase, THY10b, Tm10BH

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.76 taxane 10beta-hydroxylase