1.14.13.32: albendazole monooxygenase

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For detailed information about albendazole monooxygenase, go to the full flat file.

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Synonyms

albendazol sulfoxidase, albendazole oxidase, albendazole sulfoxidase, lancet fluke NADPH-dependent sulphoxidizing enzyme

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

1.14.13.32 albendazole monooxygenase

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2	AA Sequence
1	Application
1	CAS Registry Number
12	Cofactor
3	Inhibitors
6	KM Value [mM]
9	Localization
1	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
7	Organism
37	PDB ID
2	pH Optimum
1	Purification (Commentary)
1	Reaction
4	Reaction Type
7	Reference
9	Source Tissue
5	Specific Activity [micromol/min/mg]
10	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name
1	Temperature Stability [°C]

Systematic Name

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Systematic Name on EC 1.14.13.32 - albendazole monooxygenase

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albendazole,NADPH:oxygen oxidoreductase (sulfoxide-forming)

A microsomal flavin-containing monooxygenase. A similar conversion is also carried out by some microsomal cytochrome P-450 enzymes [EC 1.14.14.73, albendazole monooxygenase (sulfoxide-forming)]. It is estimated that cytochrome P-450s are responsible for 70% of the activity.