1.14.13.223: 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase
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Reaction
Synonyms
sibG
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Systematic Name
Systematic Name on EC 1.14.13.223 - 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase
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3-hydroxy-4-methylanthranilyl-[aryl-carrier protein],NADH:oxygen oxidoreductase (5-hydroxylating)
A flavoprotein (FAD). The enzyme, characterized from the bacterium Streptosporangium sibiricum, is involved in the biosynthesis of the antitumor antibiotic sibiromycin. The enzyme is not active with free 3-hydroxy-4-methylanthranilate.