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1.14.13.22: cyclohexanone monooxygenase

This is an abbreviated version!
For detailed information about cyclohexanone monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.22

Reaction

cyclohexanone
+
NADPH
+
H+
+
O2
=
hexano-6-lactone
+
NADP+
+
H2O

Synonyms

Bpro_556, CAMO, CHMO, ChnB, chnB protein, chnB1 protein, CHXON, CMO, cycloalkaone monooxygenase, cyclohexanone 1, 2-mono-oxygenase, cyclohexanone mono-oxygenase, cyclohexanone monooxygenase, cyclohexanone oxygenase, cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming), oxygenase, cyclohexanone mono-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.22 cyclohexanone monooxygenase

Natural Substrates Products

Natural Substrates Products on EC 1.14.13.22 - cyclohexanone monooxygenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(S)-dithiane sulfoxide + NADPH + O2
?
show the reaction diagram
-
recombinant enzyme in E. coli or Saccharomyces cerevisiae
-
-
?
1-oxa-2-oxocycloheptane + NADPH + O2
?
show the reaction diagram
-
oxidation
-
-
?
4-hydroxy-cyclohexanone + NADPH + O2
4-hydroxy-hexano-6-lactone + NADP+ + H2O
show the reaction diagram
bicyclo[3.2.0]hept-2-en-6-one + NADPH + O2
?
show the reaction diagram
cyclohexan-1,2-dione + NADPH + O2
1-oxa-2,3-dioxo-cycloheptane + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
cyclohexan-1,4-dione + NADPH + O2
1-oxa-2,5-dioxo-cycloheptane + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
cyclohexanone + NADPH + H+ + O2
epsilon-caprolactone + NADP+ + H2O
show the reaction diagram
cyclohexanone + NADPH + H+ + O2
hexano-6-lactone + NADP+ + H2O
show the reaction diagram
cyclohexanone + NADPH + O2
1-oxa-2-oxocycloheptane + NADP+ + H2O
show the reaction diagram
cyclohexanone + NADPH + O2
epsilon-caprolactone + NADP+ + H2O
show the reaction diagram
cyclohexanone + NADPH + O2
hexano-6-lactone + NADP+ + H2O
show the reaction diagram
dithiane + NADPH + H+ + O2
(R)-dithiane sulfoxide + NADP+ + H2O
show the reaction diagram
-
recombinant enzyme in E. coli or Saccharomyces cerevisiae
-
?
methyl phenyl sulfide + NADPH + H+ + O2
(R)-methyl phenyl sulfoxide + NADP+ + H2O
show the reaction diagram
n-butyl methyl sulfide + NADPH + O2
?
show the reaction diagram
-
recombinant enzyme in E. coli or Saccharomyces cerevisiae
-
-
?
tert-butyl methyl sulfide + NADPH + O2
?
show the reaction diagram
-
recombinant enzyme in E. coli or Saccharomyces cerevisiae
-
-
?
additional information
?
-