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1.14.13.215: protoasukamycin 4-monooxygenase

This is an abbreviated version!
For detailed information about protoasukamycin 4-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.215

Reaction

protoasukamycin
+
NADH
+
H+
+
O2
=
4-hydroxyprotoasukamycin
+
NAD+
+
H2O

Synonyms

asuE1, flavin-dependent protoasukamycin hydroxylase, protoasukamycin 4-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.215 protoasukamycin 4-monooxygenase

Cofactor

Cofactor on EC 1.14.13.215 - protoasukamycin 4-monooxygenase

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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
FMN
enzyme AsuE2 contains a trace amount of FMN at a molar ratio of 1:2000 (FMN:AsuE2) upon purification from Escherichia coli
additional information
enzyme AsuE1 is a flavin-dependent protoasukamycin hydroxylase, that displays no significant preference toward flavin cofactors, because FAD, FMN, and riboflavin are utilized efficiently in the catalysis
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