1.14.13.2: 4-hydroxybenzoate 3-monooxygenase

This is an abbreviated version!
For detailed information about 4-hydroxybenzoate 3-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.2

1.14.13.2

flavin

fad

fluorescens

flavoproteins

isoalloxazine

protocatechuate

3,4-dioxygenase

massey

2,4-dihydroxybenzoate

ballou

c4a-hydroperoxide

3-hydroxybenzoate

gatti

degradation

analysis

Reaction

Synonyms

4-HBA 3-hydroxylase, 4-HBA 3-monooxygenase, 4-HBA-3-hydroxylase, 4-HBMO, 4-hydroxybenzoate 3-hydroxylase, 4-hydroxybenzoate 3-monooxygenase, 4-hydroxybenzoate hydroxylase, 4-hydroxybenzoate monooxygenase, 4-hydroxybenzoic hydroxylase, 4HBA 3-hydroxylase, An_PhhA, BxeA2040, FAD-dependent 4-hydroxybenzoate hydroxylase, fungal 4-hydroxybenzoate 3-hydroxylase, HBH, m-hydroxybenzoate hydroxylase, MobA, NADPH-dependent 4-HBA hydroxylase, ncgl1032, oxygenase, 4-hydroxybenzoate 3-mono-, p-hydroxybenzoate hydroxylase, p-hydroxybenzoate-3-hydroxylase, p-hydroxybenzoic acid hydrolase, p-hydroxybenzoic acid hydroxylase, p-hydroxybenzoic hydroxylase, PaPobA, para-hydroxybenzoate hydroxylase, PHBAD, PHBH, PHBHase, PHBHCn2, phhA, PobA, pobACg, POHBase, Reut_B4006

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

1.14.13.2 4-hydroxybenzoate 3-monooxygenase

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Results	in table
8	Activating Compound
4541	AA Sequence
5	Application
1	CAS Registry Number
22	Cloned(Commentary)
96	Cofactor
17	Crystallization (Commentary)
6	Expression
43	General Information
7	General Stability
88	Inhibitors
17	kcat/KM [mM/s]
13	Ki Value [mM]
88	KM Value [mM]
1	Metals/Ions
27	Molecular Weight [Da]
57	Natural Substrates/ Products (Substrates)
170	Organism
14	Pathway
37	PDB ID
17	pH Optimum
1	pH Range
4	pH Stability
147	Protein Variants
19	Purification (Commentary)
14	Reaction
3	Reaction Type
115	Reference
16	Specific Activity [micromol/min/mg]
5	Storage Stability
208	Substrates and Products (Substrate)
32	Subunits
145	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
19	Temperature Stability [°C]
53	Turnover Number [1/s]

Expression

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Expression on EC 1.14.13.2 - 4-hydroxybenzoate 3-monooxygenase

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4-hydroxybenzoate 3-hydroxylase-encoding pobA transcripts are nearly absent in presence of benzoate and benzoate drastically decreases the transcription of this gene. Repression is mediated by pobR, the transcriptional activator of pobA gene

2 entries

enzyme expression is induced by 4-hydroxybenzoate via the transcriptional activator PobR. Addition of radish and cabbage hydrolysates to culture significantly induces the expression of the enzyme via PobR

2 entries

the enzyme is induced by 4-hydroxybenzoate as carbon source

2 entries