1.14.13.180: aklavinone 12-hydroxylase
This is an abbreviated version!
For detailed information about aklavinone 12-hydroxylase, go to the full flat file.
Reaction
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Synonyms
aklavinone 12-hydroxylase, DnrF, RdmE
ECTree
Engineering
Engineering on EC 1.14.13.180 - aklavinone 12-hydroxylase
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M56A
2fold increase in synthesis of kermesic acid
P217K
2.2fold increase in synthesis of kermesic acid
P217K/M56A
significant decrease in synthesis of kermesic acid
R373X
mutants at position Arg373 retain catalytic activity close to wild-type level
Y224F
inactive mutant enzyme