1.14.13.128: 7-methylxanthine demethylase
This is an abbreviated version!
For detailed information about 7-methylxanthine demethylase, go to the full flat file.
Word Map on EC 1.14.13.128
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1.14.13.128
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putida
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demethylation
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theophylline
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bioreactors
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uric
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coffee
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trimethyl
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costly
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1,3,7-trimethylxanthine
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rhodococcus
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paraxanthine
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3,7-dimethylxanthine
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formaldehyde
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aminopyrine
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alcaligenes
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rieske
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broad-specificity
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non-heme
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3-methylxanthine
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oxygen-dependent
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methylxanthines
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commences
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bioprocess
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klebsiella
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pharmacology
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medicine
- 1.14.13.128
- putida
-
demethylation
- theophylline
-
bioreactors
-
uric
- coffee
-
trimethyl
-
costly
- 1,3,7-trimethylxanthine
- rhodococcus
- paraxanthine
- 3,7-dimethylxanthine
- formaldehyde
- aminopyrine
- alcaligenes
-
rieske
-
broad-specificity
-
non-heme
- 3-methylxanthine
-
oxygen-dependent
- methylxanthines
-
commences
-
bioprocess
- klebsiella
- pharmacology
- medicine
Reaction
Synonyms
7-methylxanthine-specific N-demethylase, bacterial N-demethylase, caffeine demethylase, heteroxanthine demethylase, methylxanthine N-demethylase, N-demethylase, ndmA, NdmC, theobromine demethylase
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Reference
Reference on EC 1.14.13.128 - 7-methylxanthine demethylase
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Glück, M.; Lingens, F.
Heteroxanthinedemethylase, a new enzyme in the degradation of caffeine by Pseudomonas putida
Appl. Microbiol. Biotechnol.
28
59-62
1988
Pseudomonas putida
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Summers, R.M.; Louie, T.M.; Yu, C.L.; Subramanian, M.
Characterization of a broad-specificity non-haem iron N-demethylase from Pseudomonas putida CBB5 capable of utilizing several purine alkaloids as sole carbon and nitrogen source
Microbiology
157
583-592
2011
Pseudomonas putida, Pseudomonas putida CBB5
Dash, S.S.; Gummadi, S.N.
Catabolic pathways and biotechnological applications of microbial caffeine degradation
Biotechnol. Lett.
28
1993-2002
2006
Pseudomonas putida
Summers, R.M.; Louie, T.M.; Yu, C.L.; Gakhar, L.; Louie, K.C.; Subramanian, M.
Novel, highly specific N-demethylases enable bacteria to live on caffeine and related purine alkaloids
J. Bacteriol.
194
2041-2049
2012
Pseudomonas putida (M1EY73), Pseudomonas putida CBB5 (M1EY73), Pseudomonas putida CBB5
Summers, R.M.; Seffernick, J.L.; Quandt, E.M.; Yu, C.L.; Barrick, J.E.; Subramanian, M.V.
Caffeine junkie: an unprecedented glutathione S-transferase-dependent oxygenase required for caffeine degradation by Pseudomonas putida CBB5
J. Bacteriol.
195
3933-3939
2013
Pseudomonas putida (M1EY73), Pseudomonas putida CBB5 (M1EY73)
Algharrawi, K.; Summers, R.; Subramanian, M.
Production of theobromine by N-demethylation of caffeine using metabolically engineered E. coli
Biocatal. Agricult. Biotechnol.
11
153-160
2017
Pseudomonas putida (H9N289), Pseudomonas putida CBB5 (H9N289)
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Retnadhas, S.; Gummadi, S.N.
Identification and characterization of oxidoreductase component (NdmD) of methylxanthine oxygenase system in Pseudomonas sp. NCIM 5235
Appl. Microbiol. Biotechnol.
102
7913-7926
2018
Pseudomonas sp. NCIM 5235 (A0A2U9IY60)
Kim, J.H.; Kim, B.H.; Brooks, S.; Kang, S.Y.; Summers, R.M.; Song, H.K.
Structural and mechanistic insights into caffeine degradation by the bacterial N-demethylase complex
J. Mol. Biol.
431
3647-3661
2019
Pseudomonas putida (M1EY73), Pseudomonas putida CBB5 (M1EY73), Pseudomonas putida CBB5
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