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1.14.13.128: 7-methylxanthine demethylase

This is an abbreviated version!
For detailed information about 7-methylxanthine demethylase, go to the full flat file.

Word Map on EC 1.14.13.128

Reaction

7-methylxanthine
+
O2
 +
NAD(P)H
 +
H+
=
xanthine
 +
NAD(P)+
 +
H2O
 +
formaldehyde

Synonyms

7-methylxanthine-specific N-demethylase, bacterial N-demethylase, caffeine demethylase, heteroxanthine demethylase, methylxanthine N-demethylase, N-demethylase, ndmA, NdmC, theobromine demethylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.128 7-methylxanthine demethylase

KM Value

KM Value on EC 1.14.13.128 - 7-methylxanthine demethylase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0504
1,7-dimethylxanthine
-
pH 7.5, 30°C, kinetic parameters for two-subunit N-demethylase component (Ndm), in the presence of saturating amounts of Ccr (reductase component with cytochrome c reductase activity) and 50 mM Fe2+
1.1
3,7-Dimethylxanthine
-
theobromine demethylase, pH and temperature not specified in the publication
0.0153 - 0.0638
7-methylxanthine
0.037
Caffeine
pH and temperature not specified in the publication
0.113
O2
-
pH and temperature not specified in the publication