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1.14.13.127: 3-(3-hydroxyphenyl)propanoate hydroxylase

This is an abbreviated version!
For detailed information about 3-(3-hydroxyphenyl)propanoate hydroxylase, go to the full flat file.

Reaction

(2E)-3-(3-hydroxyphenyl)prop-2-enoate
+
NADH
+
H+
+
O2
=
(2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate
+
H2O
+
NAD+

Synonyms

3-(3-hydroxyphenyl)propionate hydroxylase, 3HPP 2-hydroxylase, 3HPP hydroxylase, MhpA, MhpAK-12

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.127 3-(3-hydroxyphenyl)propanoate hydroxylase

Systematic Name

Systematic Name on EC 1.14.13.127 - 3-(3-hydroxyphenyl)propanoate hydroxylase

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SYSTEMATIC NAME
IUBMB Comments
3-(3-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (2-hydroxylating)
A flavoprotein (FAD). This enzyme participates in a meta-cleavage pathway employed by the bacterium Escherichia coli for the degradation of various phenylpropanoid compounds.