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1.14.13.114: 6-hydroxynicotinate 3-monooxygenase

This is an abbreviated version!
For detailed information about 6-hydroxynicotinate 3-monooxygenase, go to the full flat file.

Reaction

6-Hydroxynicotinate
+
NADH
+
H+
+
O2
=
2,5-dihydroxypyridine
+
NAD+
+
H2O
+
CO2

Synonyms

6-hydroxynicotinic acid 3-monooxygenase, 6HNA monooxygenase, BB1770, BbNicC, NicC, PpNicC

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.114 6-hydroxynicotinate 3-monooxygenase

KI Value

KI Value on EC 1.14.13.114 - 6-hydroxynicotinate 3-monooxygenase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2.98
6-hydroxynicotinaldehyde
pH 7.5, 25°C, recombinant enzyme
0.49
nicotinate
-
-
additional information
additional information
inhibition kinetics
-