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1.14.12.14: 2-aminobenzenesulfonate 2,3-dioxygenase

This is an abbreviated version!
For detailed information about 2-aminobenzenesulfonate 2,3-dioxygenase, go to the full flat file.

Reaction

2-Aminobenzenesulfonate
+
NADH
+
H+
+
O2
=
2,3-dihydroxybenzenesulfonate
+
NH3
+
NAD+

Synonyms

2-Aminobenzenesulfonate dioxygenase, 2-Aminosulfobenzene 2,3-dioxygenase, 2AS dioxygenase, ABS-dioxygenase, ABSDOS, Oxygenase, 2-aminobenzenesulfonate di-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.14 2-aminobenzenesulfonate 2,3-dioxygenase

Natural Substrates Products

Natural Substrates Products on EC 1.14.12.14 - 2-aminobenzenesulfonate 2,3-dioxygenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
2-aminobenzenesulfonate + NADH + H+ + O2
2,3-dihydroxybenzenesulfonate + NH3 + NAD+
show the reaction diagram
2-aminobenzenesulfonate is used in the manufacture of dyes and pharmaceuticals, and, typical of xenobiotic aryl-sulfonates. The compound is degraded in few native environments, e.g. by Alcaligenes sp. strain O-1, the overall degradative process for ABS in strain O-1 is complex, overview. The pathway shows both split operons and dispersed pathway genes, and no transcriptional regulator
-
-
?
2-aminobenzenesulfonate + NADH + H+ + O2
?
show the reaction diagram
2-aminobenzenesulfonate + NADH + O2
3-sulfocatechol + NH3 + NAD+
show the reaction diagram
-
enables utilization of 2-aminobenzenesulfonate as sole carbon and energy source
-
-
?