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1.14.12.1: anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

This is an abbreviated version!
For detailed information about anthranilate 1,2-dioxygenase (deaminating, decarboxylating), go to the full flat file.

Word Map on EC 1.14.12.1

Reaction

anthranilate
+
NAD(P)H
+
H+
+
O2
=
catechol
+
CO2
+
NAD(P)+
+
NH3

Synonyms

AntDO, anthranilate hydroxylase, anthranilic acid hydroxylase, anthranilic hydroxylase, two-component anthranilate 1,2-dioxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.1 anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

Molecular Weight

Molecular Weight on EC 1.14.12.1 - anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
18900
AndAd, product of ORF4, calculated from deduced amino acid sequence
19000
-
1 * 19000 + 1 * 39000 + 1 * 54000, DNA-sequence
220000
-
gel filtration, wild type and mutant enzymes
24000
-
apha, beta, 3 * 52000 + 3 * 24000, SDS-PAGE, native mass by gel filtration
39000
-
1 * 19000 + 1 * 39000 + 1 * 54000, DNA-sequence
48000
AndAc, product of ORF3, calculated from deduced amino acid sequence
52000
-
apha, beta, 3 * 52000 + 3 * 24000, SDS-PAGE, native mass by gel filtration
54000
-
1 * 19000 + 1 * 39000 + 1 * 54000, DNA-sequence