1.14.12.1: anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

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For detailed information about anthranilate 1,2-dioxygenase (deaminating, decarboxylating), go to the full flat file.

Reaction

Synonyms

AntDO, anthranilate hydroxylase, anthranilic acid hydroxylase, anthranilic hydroxylase, two-component anthranilate 1,2-dioxygenase

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor

                1.14.12.1 anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

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Results	in table
1265	AA Sequence
1	CAS Registry Number
6	Cloned(Commentary)
12	Cofactor
2	Inhibitors
1	KM Value [mM]
1	Metals/Ions
8	Molecular Weight [Da]
20	Natural Substrates/ Products (Substrates)
49	Organism
5	Pathway
1	pH Optimum
1	pH Range
6	Protein Variants
3	Purification (Commentary)
1	Reaction
5	Reaction Type
22	Reference
35	Substrates and Products (Substrate)
4	Subunits
6	Synonyms
1	Systematic Name

Cloned

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Cloned on EC 1.14.12.1 - anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

clustered antABC genes from ADP1 chromosome encodes anthranilate dioxygenase

Acinetobacter sp.

-

396140, 439112

expressed in Escherichia coli

Acinetobacter sp.

-

439112

expressed in Escherichia coli TOP10F'

Burkholderia cepacia

Q84BZ2, Q84BZ3

659034

expressed in Escherichia coli W3110 trpD9923 cells

Pseudomonas aeruginosa

-

743231

expression of mutant enzymes in Escherichia coli BL21-Codon Plus

Acinetobacter sp.

-

657969