1.14.11.57: L-proline trans-4-hydroxylase
This is an abbreviated version!
For detailed information about L-proline trans-4-hydroxylase, go to the full flat file.
Reaction
ECTree
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Substrates Products
Substrates Products on EC 1.14.11.57 - L-proline trans-4-hydroxylase
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REACTION DIAGRAM
trans-4-hydroxy-L-proline + succinate + CO2
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L-proline + 2-oxoglutarate + O2
trans-4-hydroxy-L-proline + succinate + CO2
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L-proline + 2-oxoglutarate + O2
trans-4-hydroxy-L-proline + succinate + CO2
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the enzyme displays strict requirements for ferrous ion and 2-oxoglutarate, no cosubstrate: 2-oxopentanoate, 2-oxoadipate, pyruvate or 2-oxomalonate. L-Proline-uncoupled turnover of 2-oxoglutarate to succinate and CO2 is observed
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additional information
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the enzyme displays strict requirements for ferrous ion and 2-oxoglutarate, no cosubstrate: 2-oxopentanoate, 2-oxoadipate, pyruvate or 2-oxomalonate. L-Proline-uncoupled turnover of 2-oxoglutarate to succinate and CO2 is observed
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