1.14.11.48: xanthine dioxygenase
This is an abbreviated version!
For detailed information about xanthine dioxygenase, go to the full flat file.
Reaction
Synonyms
alpha-ketoglutarate-dependent xanthine hydroxylase, AO090001000152, TauD domain-containing protein, XanA, xanthine/alpha-ketoglutarate dioxygenase
ECTree
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Inhibitors
Inhibitors on EC 1.14.11.48 - xanthine dioxygenase
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Fe2+
-
depending on the experimental conditions, Fe2+ concentrations of above 0.025 mM can lead to enzyme inhibition of the recombinant enzyme isolated from Escherichia coli, whereas the enzyme from Aspergillus nidulans is not inhibited at Fe2+ concentrations up to 0.080 mM
-
0.5 M NaCl increases the Km of 2-oxoglutarate, increases the Km of xanthine and decreased the kcat
NaCl
decrease of up to 46% in the relative activity in presence of 0.8 M NaCl