1.14.11.3: pyrimidine-deoxynucleoside 2'-dioxygenase

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For detailed information about pyrimidine-deoxynucleoside 2'-dioxygenase, go to the full flat file.

Reaction

Synonyms

deoxyuridine 2'-dioxygenase, deoxyuridine 2'-hydroxylase, JBP1, JBP2, pyrimidine deoxyribonucleoside 2'-hydroxylase, thymidine 2'-dioxygenase, thymidine 2'-hydroxylase, thymidine 2-oxoglutarate dioxygenase, thymidine dioxygenase

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

                1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase

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12	Activating Compound
1	CAS Registry Number
1	Cloned(Commentary)
25	General Information
23	Inhibitors
8	KM Value [mM]
9	Metals/Ions
4	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
53	Organism
5	pH Optimum
5	Protein Variants
4	Purification (Commentary)
1	Reaction
4	Reaction Type
18	Reference
4	Source Tissue
3	Specific Activity [micromol/min/mg]
29	Substrates and Products (Substrate)
2	Subunits
17	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 1.14.11.3 - pyrimidine-deoxynucleoside 2'-dioxygenase

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SYSTEMATIC NAME

IUBMB Comments

2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (2'-hydroxylating)

Requires Fe(II) and ascorbate. Also acts on thymidine. cf. EC 1.14.11.10, pyrimidine-deoxynucleoside 1'-dioxygenase.