1.14.11.28: proline 3-hydroxylase

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For detailed information about proline 3-hydroxylase, go to the full flat file.

Reaction

Synonyms

C-P3H, C-P4H, collagen prolyl hydroxylases 3, collagen prolyl hydroxylases 4, L-proline-3-hydroxylase, Leprel1, Leprel2, P-3-H, P3H, P3H1, P3H2, P3H3, proline 3-hydroxylase, proline 3-hydroxylase type I, proline 3-hydroxylase type II, prolyl 3-hydrolase, prolyl 3-hydroxylase 2

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

                1.14.11.28 proline 3-hydroxylase

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Results	in table
1	Activating Compound
11	AA Sequence
2	Application
1	CAS Registry Number
3	Cloned(Commentary)
5	Cofactor
1	Crystallization (Commentary)
4	Disease/ Diagnostics
4	Expression
2	General Information
14	Inhibitors
12	KM Value [mM]
1	Localization
7	Metals/Ions
5	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
51	Organism
3	pH Optimum
2	pH Stability
3	pI Value
1	Protein Variants
5	Purification (Commentary)
1	Reaction
21	Reference
12	Source Tissue
7	Specific Activity [micromol/min/mg]
30	Substrates and Products (Substrate)
4	Subunits
33	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Temperature Stability [°C]
1	Turnover Number [1/s]

Disease

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Disease on EC 1.14.11.28 - proline 3-hydroxylase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Lymphoma

The collagen prolyl hydroxylases are novel transcriptionally silenced genes in lymphoma.

22955849

Neoplasms

The collagen prolyl hydroxylases are novel transcriptionally silenced genes in lymphoma.

22955849

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