1.14.11.18: phytanoyl-CoA dioxygenase
This is an abbreviated version!
For detailed information about phytanoyl-CoA dioxygenase, go to the full flat file.
Word Map on EC 1.14.11.18
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1.14.11.18
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peroxisomal
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refsum
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alpha-oxidation
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zellweger
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pigmentosa
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beta-oxidation
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3,7,11,15-tetramethylhexadecanoic
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punctata
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pipecolic
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rhizomelic
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pristanic
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2-hydroxyphytanoyl-coa
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chondrodysplasia
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2-hydroxylation
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anosmia
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3-methyl
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phytol
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3-methyl-branched
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cerebro-hepato-renal
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2-oxoglutarate-dependent
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diagnostics
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medicine
- 1.14.11.18
- peroxisomal
- refsum
-
alpha-oxidation
- zellweger
-
pigmentosa
-
beta-oxidation
-
3,7,11,15-tetramethylhexadecanoic
- punctata
-
pipecolic
-
rhizomelic
-
pristanic
- 2-hydroxyphytanoyl-coa
-
chondrodysplasia
-
2-hydroxylation
-
anosmia
-
3-methyl
- phytol
-
3-methyl-branched
-
cerebro-hepato-renal
-
2-oxoglutarate-dependent
- diagnostics
- medicine
Reaction
Synonyms
PAHX, PhyH, PHYHD1, Phytanic acid oxidase, phytanoyl-CoA 2-hydroxylase, Phytanoyl-CoA alpha-hydroxylase, phytanoyl-CoA dioxygenase domain containing protein 1, phytanoyl-CoA hydroxylase
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General Information
General Information on EC 1.14.11.18 - phytanoyl-CoA dioxygenase
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malfunction
physiological function
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phytanoyl-CoA dioxygenase domain-containing protein 1 plays an important role in egg shell formation of Bombyx mori
additional information
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role of 2-oxoglutarate during cyanophage infection, overview
infantile-onset Adult Refsum's disease due to phytanoyl-CoA hydroxylase ((PHYH) c.164delT, p.L55fsX12) mutation. The challenges of a successful pregnancy in a patient with Adult Refsums disease due to phytanoyl-CoA hydroxylase deficiency
malfunction
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after knocking out the PHYHD1 by using CRISPR/Cas9, the chorion genes are significantly downregulated. The silencing of PHYHD1 leads to the downregulation of many chorion protein genes, thus directly causing giant eggs