1.13.12.6: Cypridina-luciferin 2-monooxygenase
This is an abbreviated version!
For detailed information about Cypridina-luciferin 2-monooxygenase, go to the full flat file.
Word Map on EC 1.13.12.6
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1.13.12.6
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bioluminescence
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luminescence
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hilgendorfii
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luciferases
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ostracod
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firefly
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analysis
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gaussia
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diagnostics
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molecular biology
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biotechnology
- 1.13.12.6
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bioluminescence
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luminescence
- hilgendorfii
- luciferases
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ostracod
- firefly
- analysis
- gaussia
- diagnostics
- molecular biology
- biotechnology
Reaction
Synonyms
Apogon luciferase, Apogon luciferase 1, CLase, CLuc, Cypridina luciferase, Cypridina luciferin 2-monooxygenase, Cypridina noctiluca luciferase, Cypridina-type luciferase, Fbp, FBP-IgG, luciferase (Cypridina luciferin), PGE2-luciferase, Vargula luciferase
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Inhibitors
Inhibitors on EC 1.13.12.6 - Cypridina-luciferin 2-monooxygenase
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chlorpromazine
which binds to human plasma alpha 1-acid glycoprotein, shows an inhibitory effect on the luminescence of Cypridina luciferin, both in the presence of human plasma alpha 1-acid glycoprotein and a recombinant Cypridina luciferase
Cypndina gamma-globulin
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Cypridina luciferase is completely inhibited by a rabbit antibody to Cypridina luciferase
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Urea
Cypridina sp.
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at 5.0 M urea, the half-time of the enzyme is 45 min, at 6.0 M urea 8 min, and at 7.5 M urea, the enzyme is inactivated within 1 min. r´Reversible, non-competitive inhibition of the luciferase activity occurs at concentrations up to 1.5 M
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Apogon luciferase is not inhibited by a rabbit antibody to Cypridina luciferase
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additional information
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not inhibited by N-ethylmaleimide, N-methylmaleimide, iodoacetamide and p-chloromercuribenzoate
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