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1.13.12.4: lactate 2-monooxygenase

This is an abbreviated version!
For detailed information about lactate 2-monooxygenase, go to the full flat file.

Word Map on EC 1.13.12.4

Reaction

(S)-lactate
+
O2
=
acetate
 +
CO2
 +
H2O

Synonyms

L-lactate monooxygenase, L-lactate-2-monooxygenase, lactate monooxygenase, lactate oxidase, lactate oxidative decarboxylase, lactate oxygenase, lactic oxidase, lactic oxygenase, LMO

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
                1.13.12.4 lactate 2-monooxygenase

Substrates Products

Substrates Products on EC 1.13.12.4 - lactate 2-monooxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(S)-lactate + 2,6-dichlorophenolindophenol
pyruvate + ?
show the reaction diagram
-
no decarboxylation
-
-
?
(S)-lactate + methylene blue
pyruvate + ?
show the reaction diagram
-
-
-
-
?
(S)-lactate + O2
acetate + CO2 + H2O
show the reaction diagram
(S)-lactate + O2
pyruvate + H2O2
show the reaction diagram
-
G99A-mutant, no decarboxylation
-
-
?
(S)-malate + O2
oxaloacetate + H2O2
show the reaction diagram
-
-
-
?
2-hydroxy-3-butynoate + O2
?
show the reaction diagram
-
-
-
-
?
2-hydroxy-3-methylvalerate + O2
?
show the reaction diagram
-
-
-
-
?
2-hydroxybutyrate + O2
?
show the reaction diagram
-
-
-
-
?
2-hydroxycaproate + O2
?
show the reaction diagram
-
-
-
-
?
2-hydroxyisovalerate + O2
?
show the reaction diagram
-
-
-
-
?
2-hydroxyvalerate + O2
?
show the reaction diagram
-
-
-
-
?
beta-chlorolactate + electron acceptor
pyruvate + Cl- + H2O
show the reaction diagram
-
under anaerobic conditions
-
?
beta-chlorolactate + O2
chloroacetate + CO2 + H2O
show the reaction diagram
-
-
-
?
beta-phenyl-(S)-lactate + O2
?
show the reaction diagram
-
-
-
-
r
beta-phenyllactate + O2
?
show the reaction diagram
DL-2-hydroxy-3-butynoate + O2
?
show the reaction diagram
-
-
-
-
?
DL-mandelate + O2
?
show the reaction diagram
-
-
-
-
?
L-2-hydroxyisovalerate + O2
?
show the reaction diagram
-
-
-
-
r
L-alpha-hydroxy-beta-methylvalerate + O2
?
show the reaction diagram
-
-
-
-
r
L-lactate + O2
acetate + CO2 + H2O
show the reaction diagram
-
-
-
-
?