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1.13.12.4: lactate 2-monooxygenase

This is an abbreviated version!
For detailed information about lactate 2-monooxygenase, go to the full flat file.

Word Map on EC 1.13.12.4

Reaction

(S)-lactate
+
O2
=
acetate
+
CO2
+
H2O

Synonyms

L-lactate monooxygenase, L-lactate-2-monooxygenase, lactate monooxygenase, lactate oxidase, lactate oxidative decarboxylase, lactate oxygenase, lactic oxidase, lactic oxygenase, LMO

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
                1.13.12.4 lactate 2-monooxygenase

Crystallization

Crystallization on EC 1.13.12.4 - lactate 2-monooxygenase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
crystallized at 4°C in hanging drops with a reservoir solution of 0.1 M sodium citrate pH 4.6, 0.4 M lithium sulfate, and 0.4 M ammonium sulfate. Structures of Mycobacterium smegmatis wild-type enzyme and a wild-type-like C203A variant at 2.1 A and 1.7 A resolution, respectively