1.13.12.21: tetracenomycin-F1 monooxygenase

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For detailed information about tetracenomycin-F1 monooxygenase, go to the full flat file.

Reaction

Synonyms

TcmF1 monooxygenase, TmcH

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)

                1.13.12.21 tetracenomycin-F1 monooxygenase

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Results	in table
63	AA Sequence
1	Cofactor
1	General Information
4	Inhibitors
1	KM Value [mM]
1	Metals/Ions
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
2	Organism
7	Pathway
1	pH Optimum
1	pH Range
1	Purification (Commentary)
1	Reaction
2	Reference
1	Specific Activity [micromol/min/mg]
2	Substrates and Products (Substrate)
1	Subunits
2	Synonyms
1	Systematic Name

Inhibitors

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Inhibitors on EC 1.13.12.21 - tetracenomycin-F1 monooxygenase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

CuCl2

Streptomyces glaucescens

-

31% loss of activity

721576

diethyl dicarbonate

Streptomyces glaucescens

-

-

721576

N-ethylmaleimide

Streptomyces glaucescens

-

0.025 mM, complete inhibition

721576

p-chloromercuribenzoate

Streptomyces glaucescens

-

0.025 mM, complete inhibition

721576