1.13.11.75: all-trans-8'-apo-beta-carotenal 15,15'-oxygenase

This is an abbreviated version!
For detailed information about all-trans-8'-apo-beta-carotenal 15,15'-oxygenase, go to the full flat file.

Reaction

Synonyms

ACO, apo-carotenoid oxygenase, apocarotenoid cleavage oxygenase, apocarotenoid oxygenase, apocarotenoid-15,15'-oxygenase, apocarotenoid-15-15'-oxygenase, carotenoid cleavage oxygenase, CCO, Diox1, EC 1.14.99.41, More, sll1541

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.75 all-trans-8'-apo-beta-carotenal 15,15'-oxygenase

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Results	in table
9	AA Sequence
4	Cloned(Commentary)
4	Crystallization (Commentary)
5	General Information
5	Inhibitors
16	KM Value [mM]
3	Localization
4	Metals/Ions
3	Natural Substrates/ Products (Substrates)
9	Organism
39	PDB ID
2	pH Optimum
1	Protein Variants
1	Purification (Commentary)
3	Reaction
9	Reference
1	Specific Activity [micromol/min/mg]
37	Substrates and Products (Substrate)
2	Subunits
19	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
4	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.13.11.75 - all-trans-8'-apo-beta-carotenal 15,15'-oxygenase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

all-trans-8'-apo-beta-carotenal + O2

all-trans-retinal + 8'-hydroxy-15'-apocarotenal

Synechocystis sp. PCC 6803

P74334

-

765090

-

-

?

all-trans-8'-apocarotenol + O2

all-trans-retinal + (2E,4E,6E)-8-hydroxy-2,6-dimethylocta-2,4,6-trienal

Synechocystis sp. PCC 6803

P74334

-

745295

-

-

?

additional information

?

-

Synechocystis sp.

-

the substrate specificity of the enzyme is unique in that it cleaves only all-trans apocarotenoids of different chain lengths, but not C40 beta-carotene to yield all-trans C20 retinal or its derivatives

716649

-

-

?