1.13.11.71: carotenoid-9',10'-cleaving dioxygenase
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For detailed information about carotenoid-9',10'-cleaving dioxygenase, go to the full flat file.
Word Map on EC 1.13.11.71
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1.13.11.71
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retinoids
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lutein
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grey
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all-trans-retinal
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zeaxanthin
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15,15'-monooxygenase
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lycopene
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oviparous
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ornamental
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hamilton
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captive
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vitellogenesis
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loach
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queen
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strigolactone
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synthesis
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csf1r
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junglefowl
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agriculture
- 1.13.11.71
-
retinoids
- lutein
-
grey
- all-trans-retinal
- zeaxanthin
-
15,15'-monooxygenase
- lycopene
-
oviparous
-
ornamental
- hamilton
-
captive
-
vitellogenesis
- loach
-
queen
- strigolactone
- synthesis
- csf1r
- junglefowl
- agriculture
Reaction
Synonyms
BC-9',10'-oxygenase, Bcdo2, BCO2, beta,beta-carotene 9',10'-dioxygenase 2, beta,beta-carotene 9',10'-oxygenase, beta,beta-carotene-9',10'-dioxygenase, beta,beta-carotene-9',10'-dioxygenase 2, beta,beta-carotene-9,10-oxygenase 2, beta-carotene 9',10' oxygenase, beta-carotene 9',10'-oxygenase, beta-carotene-9',10'-oxygenase, beta-carotene-9,10'-oxygenase, CCD1, CCD4b, CCD7, LjCCD7, ScBCO2, xanthophyll cleavage enzyme
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Source Tissue
Source Tissue on EC 1.13.11.71 - carotenoid-9',10'-cleaving dioxygenase
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expression of the bco2 gene is dramatically decreased in prostate cancer tissue and in a range of prostate cancer cell lines as compared with nonneoplastic prostate tissue and normal prostatic epithelial cells, respectively. DNA methyltransferase inhibition induces bco2 expression in prostate cancer cells
additional information
BCO2 is highly expressed in hepatocytes and mucosal epithelium
BCO2 mRNA is detected in cell types that are known to express BCO1. BCO2 is uniquely detected in cardiac and skeletal muscle cells, prostate and endometrial connective tissue, and endocrine pancreas
additional information
expression of the genes bco1 and bco2 overlaps in the human gastrointestinal tract, but gene bco2, additionally, is expressed in several tissues neither known to be sensitive to vitamin A deficiency nor to express gene bco1
additional information
retinoid levels in the developing liver and brain at mid-gestation, overview
additional information
cellular expression and localization of BCO1 and BCO2 proteins in rat liver and intestine, immunohistochemic analysis, overview. BCO2 shows diffuse presence along epithelia with strong immunoreactivity in endothelial cells and in certain epithelial cells, possible intestinal retinoid storage cells