1.13.11.63: beta-carotene 15,15'-dioxygenase

This is an abbreviated version!
For detailed information about beta-carotene 15,15'-dioxygenase, go to the full flat file.

Reaction

Synonyms

BC-15,15'-oxygenase, BCM, BCMO, Bcmo1, Bcmo2, BCO, BCO1, BCO2, Bcox, beta,beta-carotene 15,15'-mono-oxygenase 1, beta,beta-carotene 15,15'-monooxygenase, beta,beta-carotene 15,15'-monooxygenase 1, beta,beta-carotene 15,15'-monooxygenase-1, beta,beta-carotene 15,15-monooxygenase 1, beta,beta-carotene-15,15'-monooxygenase, beta,beta-carotene-15,15'-oxygenase, beta-carotene 15,15' oxygenase, beta-carotene 15,15'-dioxygenase, beta-carotene 15,15'-monooxygenase, beta-carotene 15,15'-monooxygenase 1, beta-carotene 15,15'-oxygenase, beta-carotene 15,15-monooxygenase, beta-carotene dioxygenase 1, beta-carotene oxygenase 2, beta-carotene-15,15'-dioxygenase, beta-carotene-15,15'-monooxygenase, beta-carotene-15,15'-oxygenase, beta-carotene-15,15'-oxygenase-1, beta-carotene-15,15'-oxygenase-2, beta-CD, betaCDIOX, betaCO, BLH, brp/blh-family beta-carotene monooxygenase, brpA, carotenoid oxygenase, Ci-BCO, CMO1, EC 1.13.11.21, EC 1.14.99.36, NinaB

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.63 beta-carotene 15,15'-dioxygenase

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Results	in table
37	Activating Compound
1948	AA Sequence
8	Application
35	Cloned(Commentary)
1	Cofactor
64	Disease/ Diagnostics
11	Expression
22	General Information
3	General Stability
83	Inhibitors
5	kcat/KM [mM/s]
9	Ki Value [mM]
48	KM Value [mM]
16	Localization
20	Metals/Ions
25	Molecular Weight [Da]
58	Natural Substrates/ Products (Substrates)
96	Organism
3	Pathway
20	pH Optimum
3	pH Range
1	pI Value
34	Protein Variants
17	Purification (Commentary)
3	Reaction
20	Reaction Type
94	Reference
253	Source Tissue
7	Specific Activity [micromol/min/mg]
1	Storage Stability
155	Substrates and Products (Substrate)
21	Subunits
144	Synonyms
1	Systematic Name
16	Temperature Optimum [°C]
4	Temperature Range [°C]
4	Temperature Stability [°C]
20	Turnover Number [1/s]

General Stability

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General Stability on EC 1.13.11.63 - beta-carotene 15,15'-dioxygenase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

carotenoids stabilize the enzyme during the isolation from small intestinal mucosa

Oryctolagus cuniculus

-

438239

liver enzyme may be frozen and thawed repeatedly without loss of activity

Rattus norvegicus

-

438226

loss of activity during concentration by ultrafiltration or (NH4)2SO4 precipitation as well as during dialysis

Cavia porcellus

-

438233