1.13.11.6: 3-hydroxyanthranilate 3,4-dioxygenase

This is an abbreviated version!
For detailed information about 3-hydroxyanthranilate 3,4-dioxygenase, go to the full flat file.

Reaction

Synonyms

3-HAD, 3-HAO, 3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-hydroxyanthranilic acid oxidase, 3-hydroxyanthranilic acid oxygenase, 3-hydroxyanthranilic oxygenase, 3HAO, EC 1.13.1.6, HAD, HAO, oxygenase, 3-hydroxyanthranilate 3,4-di-

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.6 3-hydroxyanthranilate 3,4-dioxygenase

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Results	in table
1	Activating Compound
5583	AA Sequence
4	Application
1	CAS Registry Number
8	Cloned(Commentary)
1	Cofactor
6	Crystallization (Commentary)
24	Disease/ Diagnostics
8	General Information
2	General Stability
35	Inhibitors
8	Ki Value [mM]
18	KM Value [mM]
3	Localization
20	Metals/Ions
15	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
213	Organism
8	Pathway
39	PDB ID
6	pH Optimum
4	pH Range
2	pH Stability
2	pI Value
18	Protein Variants
13	Purification (Commentary)
4	Reaction
3	Reaction Type
36	Reference
20	Source Tissue
12	Specific Activity [micromol/min/mg]
8	Storage Stability
44	Substrates and Products (Substrate)
6	Subunits
22	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Temperature Range [°C]
1	Temperature Stability [°C]
5	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 1.13.11.6 - 3-hydroxyanthranilate 3,4-dioxygenase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-15°C, in 0.01 M Tris buffer, pH 7.0, 4 days, no loss of activity

Bos taurus

-

439364

-80°C, as homogenate stable for 2 months

Rattus norvegicus

-

439366

-90°C, frozen in dry ice-ethanol bath, partially purified enzyme is stable for at least 1 month, purified enzyme is unstable

Bos taurus

-

439365

0°C, 0.01 M collidine chloride, 0.01 M potassium chloride, pH 6.5, about 15% loss of activity after 1 month, purified enzyme

Bos taurus

-

439365

0°C, 66.7 mM Tris-HCl buffer, pH 8.0, 90 min, approximately 25% loss of activity

Oncorhynchus mykiss

-

439369

25°C, 66.7 mM Tris-HCl buffer, pH 8.0, 90 min, approximately 70% loss of activity

Oncorhynchus mykiss

-

439369

4°C, overnight, 75% loss of activity

Papio ursinus

-

439370

4°C, overnight, about 75% loss of activity

Bos taurus

-

439364