1.13.11.58: linoleate 9S-lipoxygenase

This is an abbreviated version!
For detailed information about linoleate 9S-lipoxygenase, go to the full flat file.

Reaction

Synonyms

15-LOX, 9-lipoxygenase, 9-LO, 9-LOX, 9LOX, 9S-lipoxygenase, arachidonate 9S-LOX, AtLOX-1, AtLOX-5, AtLOX1, AtLOX5, CaLOX1, eLOX3, epidermal lipoxygenase-3, GhLOX1, L-2, linoleate 9-lipoxygenase, linoleate 9S-lipoxygenase, linoleate 9S-lipoxygenase 1, linoleate 9S-lipoxygenase 2, linoleate 9S-lipoxygenase 3, linoleate oxygen oxidoreductase, lipoxygenase, LOX, LOX1, LOX1.1, LOX1.3, LOX12, LOX13, LOX14, LOX1:Md:1c, LOX1c, LOX2, LOX3, LOX4, LOX5, LOX6, LOX7, LOX8, LOX9, LoxA, Nb-9-LOX, Osr9-LOX1, plant LOX-1, POTLX-1, r9-LOX1, seed linoleate 9S-lipoxygenase-3, StLOX1, tuberization protein, type-1 9-LOX, ZmLOX3, ZmLOX5

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.58 linoleate 9S-lipoxygenase

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Results	in table
1	Activating Compound
63	AA Sequence
2	Application
22	Cloned(Commentary)
1	Crystallization (Commentary)
17	Disease/ Diagnostics
19	Expression
28	General Information
14	IC50 Value
15	Inhibitors
5	kcat/KM [mM/s]
11	KM Value [mM]
9	Localization
2	Metals/Ions
8	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
49	Organism
7	Pathway
13	PDB ID
12	pH Optimum
5	pH Range
5	pI Value
10	Protein Variants
11	Purification (Commentary)
1	Reaction
47	Reference
47	Source Tissue
1	Specific Activity [micromol/min/mg]
72	Substrates and Products (Substrate)
10	Subunits
118	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
3	Temperature Range [°C]
8	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.13.11.58 - linoleate 9S-lipoxygenase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

alpha-linolenate + O2

(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

2 entries

alpha-linolenic acid + O2

(10E,12Z)-9-hydroperoxy-10,12,15-octadecatrienoic acid

2 entries

linoleate + O2

(10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

5 entries

linoleate + O2

(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

6 entries

additional information

?

-

3 entries

alpha-linolenate + O2

(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Ipomoea nil

-

-

725794

-

-

?

alpha-linolenate + O2

(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Ipomoea nil Choisy

-

-

725794

-

-

?

alpha-linolenic acid + O2

(10E,12Z)-9-hydroperoxy-10,12,15-octadecatrienoic acid

Solanum tuberosum

Q43189

-

742693

-

-

?

alpha-linolenic acid + O2

(10E,12Z)-9-hydroperoxy-10,12,15-octadecatrienoic acid

Zea mays

-

-

765626

-

-

?

linoleate + O2

(10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Arabidopsis thaliana

Q06327, Q9LUW0

oxylipins produced by the 9-lipoxygenase pathway in Arabidopsis regulate lateral root development and defense responses through a specific signaling cascade

706206

-

-

?

linoleate + O2

(10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Capsicum annuum

D3TTH9

-

706336

-

-

?

linoleate + O2

(10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Capsicum annuum Nockwang

D3TTH9

-

706336

-

-

?

linoleate + O2

(10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Raphanus sativus

-

-

764903

-

-

?

linoleate + O2

(10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Zea mays

-

-

765568

-

-

?

linoleate + O2

(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Arabidopsis thaliana

-

-

726018

-

-

?

linoleate + O2

(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Arabidopsis thaliana

Q06327, Q9LUW0

oxylipins produced by the 9-lipoxygenase pathway in Arabidopsis regulate lateral root development and defense responses through a specific signaling cascade

706206

-

-

?

linoleate + O2

(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Beta vulgaris

-

regiospecificity of Nb-9-LOX, overview

725855

-

-

?

linoleate + O2

(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Malus domestica

S4UL39

-

742627

-

-

?

linoleate + O2

(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Nicotiana benthamiana

-

-

724660

-

-

?

linoleate + O2

(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate

Solanum lycopersicum

-

-

764807

-

-

?

additional information

?

-

Cynanchum gracillimum

Q4FCM5

in chitosan-treated Adelostemma gracillimum seedlings 9-LOX-derived oxylipins, namely 9,10,11-trihydroxy-12-octadecenoic acid, accumulate

725160

-

-

?

additional information

?

-

Cynanchum gracillimum

-

in chitosan-treated Adelostemma gracillimum seedlings 9-LOX-derived oxylipins, namely 9,10,11-trihydroxy-12-octadecenoic acid, accumulate

725160

-

-

?

additional information

?

-

Nicotiana benthamiana

-

Nb-9-LOX possesses both 9-lipoxygenase and 13-lipoxygenase, EC 1.13.11.12, specificity, with high predominance for the 9-LOX function

724660

-

-

?