1.13.11.34: arachidonate 5-lipoxygenase
This is an abbreviated version!
For detailed information about arachidonate 5-lipoxygenase, go to the full flat file.
Word Map on EC 1.13.11.34
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1.13.11.34
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cyclooxygenase
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prostaglandin
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leukocyte
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neutrophil
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eicosanoids
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cox-2
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asthma
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indomethacin
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ionophore
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phospholipase
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zileuton
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polymorphonuclear
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thromboxane
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flap
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airway
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peritoneal
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5-hete
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platelet
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eosinophil
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mast
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cysteinyl
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allergic
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edema
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12-lipoxygenase
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histamine
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lta4
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nordihydroguaiaretic
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lipoxygenases
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paf
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ndga
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bronchoconstriction
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5-hydroxyeicosatetraenoic
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asthmatic
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basophil
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platelet-activating
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anaphylaxis
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zymosan
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antigen-induced
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lipoxins
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montelukast
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hetes
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mpges-1
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carrageenan-induced
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a23187-stimulated
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paf-induced
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pro-resolving
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synthesis
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bronchospasm
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medicine
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drug development
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14carachidonic
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pharmacology
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bronchoconstrictors
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ulcerogenic
- 1.13.11.34
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cyclooxygenase
- prostaglandin
- leukocyte
- neutrophil
-
eicosanoids
- cox-2
- asthma
- indomethacin
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ionophore
- phospholipase
- zileuton
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polymorphonuclear
-
thromboxane
- flap
- airway
- peritoneal
-
5-hete
- platelet
-
eosinophil
-
mast
-
cysteinyl
-
allergic
- edema
-
12-lipoxygenase
- histamine
- lta4
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nordihydroguaiaretic
- lipoxygenases
- paf
- ndga
-
bronchoconstriction
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5-hydroxyeicosatetraenoic
-
asthmatic
-
basophil
-
platelet-activating
- anaphylaxis
- zymosan
-
antigen-induced
-
lipoxins
- montelukast
-
hetes
- mpges-1
-
carrageenan-induced
-
a23187-stimulated
-
paf-induced
-
pro-resolving
- synthesis
- bronchospasm
- medicine
- drug development
-
14carachidonic
- pharmacology
-
bronchoconstrictors
-
ulcerogenic
Reaction
Synonyms
5-lipoxygenase, 5-LO, 5-LO1, 5-LOX, 5DELTA-lipoxygenase, 5LO, 5LOX-1, ALOX5, arachidonate 5-LO, arachidonate:oxygen oxidoreductase, arachidonic 5-lipoxygenase, arachidonic acid 5-lipoxygenase, C-5-lipoxygenase, DELTA5-lipoxygenase, H5-LO, leukotriene A4 synthase, leukotriene-A4 synthase, lipoxygenase 15, lipoxygenase 5, lipoxygenase-1, LO-1, LOX-15, LOX-5, LTA synthase, LTA4 synthase, oxygenase, arachidonate, 5-lip-, PMNL 5-lipoxygenase
ECTree
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KI Value
KI Value on EC 1.13.11.34 - arachidonate 5-lipoxygenase
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0.0019
(17S)-hydroperoxy-4,7,10,13,15,19-docosahexaenoyl lysophosphatidylcholine
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pH 6.3, 25°C
0.00071
(2,4-dihydroxyphenyl)[3-(1-[hydroxy[(3,4,5-trihydroxyphenyl)methyl]amino]ethyl)phenyl]methanone
pH and temperature not specified in the publication
0.0009
(2,4-dihydroxyphenyl)[3-(1-[hydroxy[(4-hydroxyphenyl)methyl]amino]ethyl)phenyl]methanone
pH and temperature not specified in the publication
0.016
2-(3-acetylphenyl)propanoic acid
pH and temperature not specified in the publication
0.00136
2-(3-benzoylphenyl)propanoic acid
pH and temperature not specified in the publication
0.00267
2-(3-phenoxyphenyl)propanoic acid
pH and temperature not specified in the publication
0.0455
2-methyl-3-[(morpholine-4-carbonyl)amino]-3-oxopropanoic acid
pH and temperature not specified in the publication
0.00734
2-[3-(2-methylpropanoyl)phenyl]propanoic acid
pH and temperature not specified in the publication
0.00734
2-[3-(morpholine-4-carbonyl)phenyl]propanoic acid
pH and temperature not specified in the publication
0.00042
2-[3-[(4-hydroxyphenyl)carbamoyl]phenyl]propanoic acid
pH and temperature not specified in the publication
0.0057
2-[3-[hydroxy(phenyl)amino]phenyl]propanoic acid
pH and temperature not specified in the publication
0.00013
2-[4'-[(morpholin-4-yl)sulfanyl][1,1'-biphenyl]-3-yl]propanoic acid
pH and temperature not specified in the publication
0.0112
2-[4-(morpholine-4-carbonyl)phenyl]propanoic acid
pH and temperature not specified in the publication
0.17
3-(1-carboxyethyl)benzoic acid
pH and temperature not specified in the publication
0.00515
4-[(hydroxy[1-[3'-(morpholin-4-yl)[1,1'-biphenyl]-3-yl]ethyl]amino)methyl]phenol
pH and temperature not specified in the publication
0.00011
4-[[hydroxy(2-methyl-1-[3-[(morpholin-4-yl)oxy]phenyl]propyl)amino]methyl]phenol
pH and temperature not specified in the publication
0.00032
5-[[hydroxy(2-methyl-1-[3-[(morpholin-4-yl)oxy]phenyl]propyl)amino]methyl]benzene-1,2,3-triol
pH and temperature not specified in the publication
0.0016
delta-tocopherol-13'-carboxychromanol
pH not specified in the publication, temperature not specified in the publication
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0.0022
delta-tocotrienol
pH not specified in the publication, temperature not specified in the publication
0.0008
delta-tocotrienol-13'-carboxychromanol
pH not specified in the publication, temperature not specified in the publication
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0.00059
[3-(1-[hydroxy[(3,4,5-trihydroxyphenyl)methyl]amino]ethyl)phenyl](morpholin-4-yl)methanone
pH and temperature not specified in the publication
0.00018
[3-(1-[hydroxy[(4-hydroxyphenyl)methyl]amino]ethyl)phenyl](morpholin-4-yl)methanone
pH and temperature not specified in the publication
0.0398
[3-(bromocarbonyl)phenyl](morpholin-4-yl)acetic acid
pH and temperature not specified in the publication
additional information
additional information
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inhibition kinetics, overview
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