1.13.11.26: peptide-tryptophan 2,3-dioxygenase

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For detailed information about peptide-tryptophan 2,3-dioxygenase, go to the full flat file.

Reaction

Synonyms

peptidyltryptophan 2,3-dioxygenase, pyrrolooxygenase, tryptophan pyrrolooxygenase, tryptophan-2,3-dioxygenase

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.26 peptide-tryptophan 2,3-dioxygenase

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Results	in table
1	CAS Registry Number
1	Cofactor
20	Inhibitors
4	KM Value [mM]
4	Metals/Ions
1	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
10	Organism
5	pH Optimum
4	Purification (Commentary)
1	Reaction
3	Reaction Type
10	Reference
11	Source Tissue
4	Specific Activity [micromol/min/mg]
3	Storage Stability
29	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
1	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 1.13.11.26 - peptide-tryptophan 2,3-dioxygenase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

D-tryptophan + O2

formylkynurenine

Triticum aestivum

-

-

439517, 439522, 439524

-

-

?

DL-5-fluorotryptophan + O2

5-fluoroformylkynurenine

Triticum aestivum

-

-

439517

-

-

?

DL-5-methyltryptophan + O2

5-methyl-N-formylkynurenine

Triticum aestivum

-

-

439517

-

-

?

DL-6-fluorotryptophan + O2

4-fluoro-N-formylkynurenine

Triticum aestivum

-

-

439517

-

-

?

DL-6-methyltryptophan + O2

4-methyl-N-formylkynurenine

Triticum aestivum

-

-

439517

-

-

?

DL-7-methyltryptophan + O2

3-methyl-N-formylkynurenine

Triticum aestivum

-

-

439517

-

-

?

DL-tryptophan + O2

formylkynurenine

Triticum aestivum

-

-

439517

-

-

?

DL-tryptophan methyl ester + O2

formylkynurenine methyl ester

Triticum aestivum

-

-

439517

-

-

?

ethyl N-acetyl-L-tryptophan + O2

ethyl 2-acetamido-3-2'-formimidobenzoyl propionate

2 entries

L-5-hydroxytryptophan + O2

5-hydroxy-N-formylkynurenine

Triticum aestivum

-

very poor substrate activity with molecular form A

439517

-

-

?

L-tryptophan + O2

formylkynurenine

4 entries

L-tryptophan methyl ester + O2

N-formylkynurenine methyl ester

Triticum aestivum

-

-

439518

-

-

?

N-acetyl-5-methyltryptophan + O2

5-methyl-Nalpha-acetyl-Nomega-formylkynurenine

Triticum aestivum

-

-

439517

-

-

?

N-acetyl-DL-tryptophan + O2

N-acetylformylkynurenine

Triticum aestivum

-

-

439517

-

-

?

N-acetyltryptophan + O2

Nalpha-acetyl-Nomega-formylkynurenine

Triticum aestivum

-

-

439518, 439521, 439522

-

-

?

tryptophan + O2

L-kynurenine

Rattus norvegicus

-

-

439525

-

439525

?

ethyl N-acetyl-L-tryptophan + O2

ethyl 2-acetamido-3-2'-formimidobenzoyl propionate

Triticum aestivum

-

-

439522, 439523

-

-

?

ethyl N-acetyl-L-tryptophan + O2

ethyl 2-acetamido-3-2'-formimidobenzoyl propionate

Triticum aestivum

-

-

439524

-

439524

?

L-tryptophan + O2

formylkynurenine

Capsicum annuum

-

-

439519

-

-

?

L-tryptophan + O2

formylkynurenine

Rattus norvegicus

-

-

439525

-

-

?

L-tryptophan + O2

formylkynurenine

Triticum aestivum

-

-

439517, 439518, 439521, 439522, 439524

-

-

?

L-tryptophan + O2

formylkynurenine

Triticum aestivum

-

enzyme extract of whole flour

439520

-

-

?