1.13.11.11: tryptophan 2,3-dioxygenase

This is an abbreviated version!
For detailed information about tryptophan 2,3-dioxygenase, go to the full flat file.

Reaction

Synonyms

33737, BRAFLDRAFT_210874, C28H8.11, EC 1.11.1.4, hTDO, IDO-1, IDO-2, IDO1, IDO2, indoleamine 2,3-dioxygenase 1, indoleamine 2,3-dioxygenase 2, TDO, TDO2, TDOa, tryptophan 2,3-dioxygenase, tryptophan 2,3-dioxygenase 2, tryptophan 2,3-dioxygenase-2, tryptophan-2,3-dioxygenase, v1g157887, vCG5163, XcTDO

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.11 tryptophan 2,3-dioxygenase

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Results	in table
2	Activating Compound
9810	AA Sequence
2	Application
14	Cloned(Commentary)
18	Cofactor
4	Crystallization (Commentary)
1191	Disease/ Diagnostics
4	Expression
54	General Information
4	General Stability
135	IC50 Value
146	Inhibitors
26	KM Value [mM]
1	Localization
4	Metals/Ions
3	Molecular Weight [Da]
39	Natural Substrates/ Products (Substrates)
55	Organism
9	Pathway
85	PDB ID
9	pH Optimum
3	Posttranslational Modification
24	Protein Variants
5	Purification (Commentary)
3	Reaction
45	Reference
63	Source Tissue
60	Substrates and Products (Substrate)
9	Subunits
64	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
8	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 1.13.11.11 - tryptophan 2,3-dioxygenase

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MOLECULAR WEIGHT

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

192000

Homo sapiens

P48775

in the presence of tryptophan, tetramer, gel filtration

765688

48000

Homo sapiens

P48775

in the absence of tryptophan, inactive monomer, gel filtration

765688

96000

Homo sapiens

P48775

in the absence of tryptophan, inactive dimer, gel filtration

765688