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BRENDA support

1.11.1.6: catalase

This is an abbreviated version!
For detailed information about catalase, go to the full flat file.

Word Map on EC 1.11.1.6

Reaction

2 H2O2 =

O2
+ 2 H2O

Synonyms

Ab-catalase, BNC, caperase, CAT, CAT-1, CAT-A, CAT-P, Cat1.4, CatA, catalase, catalase A, catalase C, catalase form III, catalase P, catalase-1, catalase-A, catalase-peroxidase, catalase-phenol oxidase, CatB, CATC, CatF, CatG, CatP, CATPO, CcmC, CP, equilase, H2O2:H2O2 oxidoreductase, haem catalase, HPI-A, HPI-B, HPII, HTHP, hydrogen peroxide oxidoreductase, KAT, Kat E catalase, KatA, KatB, KatC, KatP, KpA, manganese catalase, More, optidase, PktA, polyethylene glycol-catalase, tyrosine-coordinated heme protein, VktA

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.6 catalase

Source Tissue

Source Tissue on EC 1.11.1.6 - catalase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
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epithelial cell
Manually annotated by BRENDA team
constitutive expression for the first 3 h post injection of H2O2
Manually annotated by BRENDA team
-
Y-1 cell, increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms
Manually annotated by BRENDA team
catalase activity is significantly higher in patients with renal cell carcinoma than in controls
Manually annotated by BRENDA team
-
Caco-2 cell, increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms
Manually annotated by BRENDA team
-
the catalase activity in striatum is significantly decreased in the lesioned group as compared to sham group and pretreatment with Withania somnifera reverses its activity significantly and dose dependently in the lesioned goup pretretaed with 100 mg/kg 200 mg/ml or 300 mg/kg body weight extracts of Withania somnifera orally as compared to lesioned group
Manually annotated by BRENDA team
-
heme in the growth medium is absolutely required for enzyme expression
Manually annotated by BRENDA team
expression is highest 4–6 h after cyst germination
Manually annotated by BRENDA team
-
zygotic
Manually annotated by BRENDA team
-
from seeds
Manually annotated by BRENDA team
-
293 cell
Manually annotated by BRENDA team
-
56 genotypes
Manually annotated by BRENDA team
highest levels of transcripts in hepatopancreas, followed by a little lower expression in hemocytes and moderate expression in the tissues of brain, eyestalk, gill, intestine and muscle, with the lowest expression in the heart
Manually annotated by BRENDA team
-
diabetic animals treated with BioGHK incorporated collagen (Peptide Incorporated Collagen) show significant higher levels of catalase due to the ability of GHK to attract macrophages and cytokines towards the wound environment
Manually annotated by BRENDA team
-
overexpression of hepatitis C virus non-structural proteins increases catalase activity
Manually annotated by BRENDA team
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catalase activity is decreased dramatically after forebrain ischemia insult, no significant difference in catalase activity between control group and sham-operated group and curcumin-treted group
Manually annotated by BRENDA team
-
spadix
Manually annotated by BRENDA team
-
telomerase-deficient MEF cells have lower catalase activity
Manually annotated by BRENDA team
-
mouse small mesenteric artery
Manually annotated by BRENDA team
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retinal. mRNA transcript for catalase in normal (5.5 mM) glucose medium or high (22 mM) glucose medium after 1, 3, or 5 days of stimulation. The pattern of relative expression of the pericyte catalase transcript at day 1 is essentially unchanged at 3 and 5 days with only a slightly higher value (10%) in high glucose medium, which is statistically significantly increased after 1 (p = 0.037), 3 (p = 0.037), and 5 (p = 0.025) days
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
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from seeds
Manually annotated by BRENDA team
-
catalase activity is reduced significantly by lesioning, extract of Ginkgo biloba dose-dependently restores the activity
Manually annotated by BRENDA team
-
clone T-47DN5
Manually annotated by BRENDA team
additional information