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1.11.1.16: versatile peroxidase

This is an abbreviated version!
For detailed information about versatile peroxidase, go to the full flat file.

Word Map on EC 1.11.1.16

Reaction

1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol
+
H2O2
=
4-hydroxy-3-methoxybenzaldehyde
+
2-methoxyphenol
+
glycolaldehyde
+
H2O

Synonyms

B-type dye-decolorizing peroxidase, bacterial lignin peroxidase, DypB, manganese peroxidase 4, Mb peroxidase, metMb peroxidase, Mnp4, More, myoglobin, R1B4, versatile peroxidase, versatile peroxidase MnP2, versatile peroxidase VPL2 precursor, VP1, Vpl2, VPS1

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.16 versatile peroxidase

Reference

Reference on EC 1.11.1.16 - versatile peroxidase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mester, T.; Field, J.A.
Characterization of a novel manganese peroxidase-lignin peroxidase hybrid isozyme produced by Bjerkandera species strain BOS55 in the absence of manganese
J. Biol. Chem.
273
15412-15417
1998
Bjerkandera sp., Bjerkandera sp. BOS55
Manually annotated by BRENDA team
Martinez, M.J.; Ruiz-Duenas, F.J.; Guillen, F.; Martinez, A.T.
Purification and catalytic properties of two manganese peroxidase isoenzymes from Pleurotus eryngii
Eur. J. Biochem.
237
424-432
1996
Pleurotus eryngii
Manually annotated by BRENDA team
Kamitsuji, H.; Watanabe, T.; Honda, Y.; Kuwahara, M.
Direct oxidation of polymeric substrates by multifunctional manganese peroxidase isoenzyme from Pleurotus ostreatus without redox mediators
Biochem. J.
386
387-393
2005
Pleurotus ostreatus
Manually annotated by BRENDA team
Cohen, R.; Persky, L.; Hazan-Eitan, Z.; Yarden, O.; Hadar, Y.
Mn2+ alters peroxidase profiles and lignin degradation by the white-rot fungus Pleurotus ostreatus under different nutritional and growth conditions
Appl. Biochem. Biotechnol.
102-103
415-429
2002
Pleurotus ostreatus
Manually annotated by BRENDA team
Ruiz-Duenas, F.J.; Guillen, F.; Camarero, S.; Perez-Boada, M.; Martinez, M.J.; Martinez, A.T.
Regulation of peroxidase transcript levels in liquid cultures of the ligninolytic fungus Pleurotus eryngii
Appl. Environ. Microbiol.
65
4458-4463
1999
Pleurotus eryngii
Manually annotated by BRENDA team
Ruiz-Duenas, F.J.; Martinez, M.J.; Martinez, A.T.
Heterologous expression of Pleurotus eryngii peroxidase confirms its ability to oxidize Mn(2+) and different aromatic substrates
Appl. Environ. Microbiol.
65
4705-4707
1999
Pleurotus eryngii (O94753)
Manually annotated by BRENDA team
Ruiz-Duenas, F.J.; Camarero, S.; Perez-Boada, M.; Martinez, M.J.; Martinez, A.T.
A new versatile peroxidase from Pleurotus
Biochem. Soc. Trans.
29
116-122
2001
Pleurotus eryngii
Manually annotated by BRENDA team
Pogni, R.; Baratto, M.C.; Giansanti, S.; Teutloff, C.; Verdin, J.; Valderrama, B.; Lendzian, F.; Lubitz, W.; Vazquez-Duhalt, R.; Basosi, R.
Tryptophan-based radical in the catalytic mechanism of versatile peroxidase from Bjerkandera adusta
Biochemistry
44
4267-4274
2005
Bjerkandera adusta
Manually annotated by BRENDA team
Verdin, J.; Pogni, R.; Baeza, A.; Baratto, M.C.; Basosi, R.; Vazquez-Duhalt, R.
Mechanism of versatile peroxidase inactivation by Ca(2+) depletion
Biophys. Chem.
121
163-170
2006
Bjerkandera adusta
Manually annotated by BRENDA team
Wang, Y.; Vazquez-Duhalt, R.; Pickard, M.A.
Manganese-lignin peroxidase hybrid from Bjerkandera adusta oxidizes polycyclic aromatic hydrocarbons more actively in the absence of manganese
Can. J. Microbiol.
49
675-682
2003
Bjerkandera adusta
Manually annotated by BRENDA team
Gomez-Toribio, V.; Martinez, A.T.; Martinez, M.J.; Guillen, F.
Oxidation of hydroquinones by the versatile ligninolytic peroxidase from Pleurotus eryngii. H2O2 generation and the influence of Mn2+
Eur. J. Biochem.
268
4787-4793
2001
Pleurotus eryngii
Manually annotated by BRENDA team
Camarero, S.; Ruiz-Duenas, F.J.; Sarkar, S.; Martinez, M.J.; Martinez, A.T.
The cloning of a new peroxidase found in lignocellulose cultures of Pleurotus eryngii and sequence comparison with other fungal peroxidases
FEMS Microbiol. Lett.
191
37-43
2000
Pleurotus eryngii (Q9UVP6), Pleurotus eryngii
Manually annotated by BRENDA team
Camarero, S.; Sarkar, S.; Ruiz-Duenas, F.J.; Martinez, M.J.; Martinez, A.T.
Description of a versatile peroxidase involved in the natural degradation of lignin that has both manganese peroxidase and lignin peroxidase substrate interaction sites
J. Biol. Chem.
274
10324-10330
1999
Pleurotus eryngii
Manually annotated by BRENDA team
Pogni, R.; Baratto, M.C.; Teutloff, C.; Giansanti, S.; Ruiz-Duenas, F.J.; Choinowski, T.; Piontek, K.; Martinez, A.T.; Lendzian, F.; Basosi, R.
A tryptophan neutral radical in the oxidized state of versatile peroxidase from Pleurotus eryngii: a combined multifrequency EPR and density functional theory study
J. Biol. Chem.
281
9517-9526
2006
Pleurotus eryngii (O94753), Pleurotus eryngii
Manually annotated by BRENDA team
Banci, L.; Camarero, S.; Martinez, A.T.; Martinez, M.J.; Perez-Boada, M.; Pierattelli, R.; Ruiz-Duenas, F.J.
NMR study of manganese(II) binding by a new versatile peroxidase from the white-rot fungus Pleurotus eryngii
J. Biol. Inorg. Chem.
8
751-760
2003
Pleurotus eryngii
Manually annotated by BRENDA team
Perez-Boada, M.; Ruiz-Duenas, F.J.; Pogni, R.; Basosi, R.; Choinowski, T.; Martinez, M.J.; Piontek, K.; Martinez, A.T.
Versatile peroxidase oxidation of high redox potential aromatic compounds: site-directed mutagenesis, spectroscopic and crystallographic investigation of three long-range electron transfer pathways
J. Mol. Biol.
354
385-402
2005
Pleurotus eryngii
Manually annotated by BRENDA team
Tsukihara, T.; Honda, Y.; Watanabe, T.
Molecular breeding of white rot fungus Pleurotus ostreatus by homologous expression of its versatile peroxidase MnP2
Appl. Microbiol. Biotechnol.
71
114-120
2006
Pleurotus ostreatus
Manually annotated by BRENDA team
Ruiz-Duenas, F.J.; Morales, M.; Perez-Boada, M.; Choinowski, T.; Martinez, M.J.; Piontek, K.; Martinez, A.T.
Manganese oxidation site in Pleurotus eryngii versatile peroxidase: a site-directed mutagenesis, kinetic, and crystallographic study
Biochemistry
46
66-77
2007
Pleurotus eryngii (O94753), Pleurotus eryngii
Manually annotated by BRENDA team
Tsukihara, T.; Honda, Y.; Sakai, R.; Watanabe, T.; Watanabe, T.
Exclusive overproduction of recombinant versatile peroxidase MnP2 by genetically modified white rot fungus, Pleurotus ostreatus
J. Biotechnol.
126
431-439
2006
Pleurotus ostreatus
Manually annotated by BRENDA team
Tsukihara, T.; Honda, Y.; Sakai, R.; Watanabe, T.; Watanabe, T.
Mechanism for oxidation of high-molecular-weight substrates by a fungal versatile peroxidase, MnP2
Appl. Environ. Microbiol.
74
2873-2881
2008
Pleurotus ostreatus
Manually annotated by BRENDA team
Ruiz-Duenas, F.J.; Morales, M.; Mate, M.J.; Romero, A.; Martinez, M.J.; Smith, A.T.; Martinez, A.T.
Site-directed mutagenesis of the catalytic tryptophan environment in Pleurotus eryngii versatile peroxidase
Biochemistry
47
1685-1695
2008
Pleurotus eryngii (O94753), Pleurotus eryngii
Manually annotated by BRENDA team
Eibes, G.M.; Lu-Chau, T.A.; Ruiz-Duenas, F.J.; Feijoo, G.; Martinez, M.J.; Martinez, A.T.; Lema, J.M.
Effect of culture temperature on the heterologous expression of Pleurotus eryngii versatile peroxidase in Aspergillus hosts
Bioprocess Biosyst. Eng.
32
129-134
2009
Pleurotus eryngii
Manually annotated by BRENDA team
Mohorcic, M.; Bencina, M.; Friedrich, J.; Jerala, R.
Expression of soluble versatile peroxidase of Bjerkandera adusta in Escherichia coli
Biores. Technol.
100
851-858
2009
Bjerkandera adusta (A5JTV4), Bjerkandera adusta
Manually annotated by BRENDA team
Moreira, P.R.; Almeida-Vara, E.; Malcata, F.X.; Duarte, J.C.
Lignin transformation by a versatile peroxidase from a novel Bjerkandera sp. strain
Int. Biodeter. Biodegrad.
59
234-238
2007
Bjerkandera sp.
-
Manually annotated by BRENDA team
Tinoco, R.; Verdin, J.; Vazquez-Duhalt, R.
Role of oxidizing mediators and tryptophan 172 in the decoloration of industrial dyes by the versatile peroxidase from Bjerkandera adusta
J. Mol. Catal. B
46
1-7
2007
Bjerkandera adusta
-
Manually annotated by BRENDA team
Ruiz-Duenas, F.J.; Pogni, R.; Morales, M.; Giansanti, S.; Mate, M.J.; Romero, A.; Martinez, M.J.; Basosi, R.; Martinez, A.T.
Protein radicals in fungal versatile peroxidase: catalytic tryptophan radical in both compound I and compound II and studies on W164Y, W164H, and W164S variants
J. Biol. Chem.
284
7986-7994
2009
Pleurotus eryngii (O94753), Pleurotus eryngii
Manually annotated by BRENDA team
Ruiz-Duenas, F.J.; Morales, M.; Garcia, E.; Miki, Y.; Martinez, M.J.; Martinez, A.T.
Substrate oxidation sites in versatile peroxidase and other basidiomycete peroxidases
J. Exp. Bot.
60
441-452
2009
Pleurotus eryngii (O94753)
Manually annotated by BRENDA team
Marques, G.; Gamelas, J.A.; Ruiz-Duenas, F.J.; del Rio, J.C.; Evtuguin, D.V.; Martinez, A.T.; Gutierrez, A.
Delignification of eucalypt kraft pulp with manganese-substituted polyoxometalate assisted by fungal versatile peroxidase
Biores. Technol.
101
5935-5940
2010
Pleurotus eryngii
Manually annotated by BRENDA team
Taboada-Puig, R.; Lu-Chau, T.A.; Moreira, M.T.; Feijoo, G.; Lema, J.M.
Activation of Kraft lignin by an enzymatic treatment with a versatile peroxidase from Bjerkandera sp. R1
Appl. Biochem. Biotechnol.
169
1262-1278
2013
Bjerkandera sp., Bjerkandera sp. R1
Manually annotated by BRENDA team
Santos, A.; Mendes, S.; Brissos, V.; Martins, L.
New dye-decolorizing peroxidases from Bacillus subtilis and Pseudomonas putida MET94: towards biotechnological applications
Appl. Microbiol. Biotechnol.
98
2053-2065
2013
Pseudomonas putida, Pseudomonas putida MET94
Manually annotated by BRENDA team
Garcia-Ruiz, E.; Gonzalez-Perez, D.; Ruiz-Duenas, F.J.; Martinez, A.T.; Alcalde, M.
Directed evolution of a temperature-, peroxide- and alkaline pH-tolerant versatile peroxidase
Biochem. J.
441
487-498
2012
Pleurotus eryngii (O94753), Pleurotus eryngii
Manually annotated by BRENDA team
Sezer, M.; Santos, A.; Kielb, P.; Pinto, T.; Martins, L.O.; Todorovic, S.
Distinct structural and redox properties of the heme active site in bacterial dye decolorizing peroxidase-type peroxidases from two subfamilies: resonance Raman and electrochemical study
Biochemistry
52
3074-3084
2013
Pseudomonas putida, Pseudomonas putida MET94
Manually annotated by BRENDA team
Ertan, H.; Siddiqui, K.S.; Muenchhoff, J.; Charlton, T.; Cavicchioli, R.
Kinetic and thermodynamic characterization of the functional properties of a hybrid versatile peroxidase using isothermal titration calorimetry: Insight into manganese peroxidase activation and lignin peroxidase inhibition
Biochimie
94
1221-1231
2012
Bjerkandera adusta
Manually annotated by BRENDA team
Bao, X.; Liu, A.; Lu, X.; Li, J.J.
Direct over-expression, characterization and H2O2 stability study of active Pleurotus eryngii versatile peroxidase in Escherichia coli
Biotechnol. Lett.
34
1537-1543
2012
Pleurotus eryngii (O94753), Pleurotus eryngii
Manually annotated by BRENDA team
Contreras, E.; Urra, J.; Vasquez, C.; Palma, C.
Detoxification of azo dyes mediated by cell-free supernatant culture with manganese-dependent peroxidase activity: effect of Mn2+ concentration and H2O2 dose
Biotechnol. Prog.
28
114-120
2012
Phanerodontia chrysosporium, Phanerodontia chrysosporium BKM-F-1767
Manually annotated by BRENDA team
Pozdnyakova, N.; Makarov, O.; Chernyshova, M.; Turkovskaya, O.; Jarosz-Wilkolazka, A.
Versatile peroxidase of Bjerkandera fumosa: substrate and inhibitor specificity
Enzyme Microb. Technol.
52
44-53
2013
Bjerkandera fumosa
Manually annotated by BRENDA team
Singh, R.; Grigg, J.C.; Armstrong, Z.; Murphy, M.E.; Eltis, L.D.
Distal heme pocket residues of B-type dye-decolorizing peroxidase: arginine but not aspartate is essential for peroxidase activity
J. Biol. Chem.
287
10623-10630
2012
Rhodococcus jostii (Q0SE24)
Manually annotated by BRENDA team
Morales, M.; Mate, M.J.; Romero, A.; Martinez, M.J.; Martinez, A.T.; Ruiz-Duenas, F.J.
Two oxidation sites for low redox potential substrates: a directed mutagenesis, kinetic, and crystallographic study on Pleurotus eryngii versatile peroxidase
J. Biol. Chem.
287
41053-41067
2012
Pleurotus eryngii (O94753), Pleurotus eryngii
Manually annotated by BRENDA team
Praveen, K.; Usha, K.Y.; Viswanath, B.; Reddy, B.R.
Kinetic properties of manganese peroxidase from the mushroom Stereum ostrea and its ability to decolorize dyes
J. Microbiol. Biotechnol.
22
1540-1548
2012
Stereum ostrea
Manually annotated by BRENDA team
Salame, T.; Knop, D.; Levinson, D.; Mabjeesh, S.; Yarden, O.; Hadar, Y.
Release of Pleurotus ostreatus versatile-peroxidase from Mn2+ repression enhances anthropogenic and natural substrate degradation
PLoS ONE
7
e52446
2012
Pleurotus ostreatus (Q96V56)
Manually annotated by BRENDA team
Taboada-Puig, R.; Lu-Chau, T.; Moreira, M.; Feijoo, G.; Martinez, M.; Lema, J.
A new strain of Bjerkandera sp. production, purification and characterization of versatile peroxidase
World J. Microbiol. Biotechnol.
27
115-122
2011
Bjerkandera sp.
Manually annotated by BRENDA team
Gonzalez-Perez, D.; Garcia-Ruiz, E.; Ruiz-Duenas, F.; Martinez, A.; Alcalde, M.
Structural determinants of oxidative stabilization in an evolved versatile peroxidase
ACS Catal.
4
3891-3901
2014
Pleurotus eryngii (O94753)
-
Manually annotated by BRENDA team
Mendez-Hernandez, J.E.; Eibes, G.; Arca-Ramos, A.; Lu-Chau, T.A.; Feijoo, G.; Moreira, M.T.; Lema, J.M.
Continuous removal of nonylphenol by versatile peroxidase in a two-stage membrane bioreactor
Appl. Biochem. Biotechnol.
175
3038-3047
2015
Bjerkandera sp., Bjerkandera sp. R1
Manually annotated by BRENDA team
Knop, D.; Levinson, D.; Makovitzki, A.; Agami, A.; Lerer, E.; Mimran, A.; Yarden, O.; Hadar, Y.
Limits of versatility of versatile peroxidase
Appl. Environ. Microbiol.
82
4070-4080
2016
Pleurotus ostreatus, Pleurotus ostreatus PC9
Manually annotated by BRENDA team
Taboada-Puig, R.; Lu-Chau, T.A.; Eibes, G.; Feijoo, G.; Moreira, M.T.; Lema, J.M.
Continuous removal of endocrine disruptors by versatile peroxidase using a two-stage system
Biotechnol. Prog.
31
908-916
2015
Bjerkandera adusta, Bjerkandera adusta ATCC 90940
Manually annotated by BRENDA team
Ravichandran, A.; Sridhar, M.
Insights into the mechanism of lignocellulose degradation by versatile peroxidases
Curr. Sci.
113
35-42
2017
Bjerkandera adusta, Pleurotus eryngii, Pleurotus ostreatus, Bjerkandera fumosa
-
Manually annotated by BRENDA team
Imami, A.; Riemer, S.; Schulze, M.; Amelung, F.; Gorshkov, V.; Ruehl, M.; Ammenn, J.; Zorn, H.
Depolymerization of lignosulfonates by submerged cultures of the basidiomycete Irpex consors and cloning of a putative versatile peroxidase
Enzyme Microb. Technol.
81
8-15
2015
Cerrena consors
Manually annotated by BRENDA team
Siddiqui, K.S.; Ertan, H.; Charlton, T.; Poljak, A.; Daud Khaled, A.K.; Yang, X.; Marshall, G.; Cavicchioli, R.
Versatile peroxidase degradation of humic substances use of isothermal titration calorimetry to assess kinetics, and applications to industrial wastes
J. Biotechnol.
178
1-11
2014
Bjerkandera adusta
Manually annotated by BRENDA team
Schüttmann, I.; Bouws, H.; Szweda, R.; Suckow, M.; Czermak, P.; Zorn, H.
Induction, characterization, and heterologous expression of a carotenoid degrading versatile peroxidase from Pleurotus sapidus
J. Mol. Catal. B
103
79-84
2014
Pleurotus sapidus (Q4QZ27)
-
Manually annotated by BRENDA team
Saez-Jimenez, V.; Fernandez-Fueyo, E.; Medrano, F.J.; Romero, A.; Martinez, A.T.; Ruiz-Duenas, F.J.
Improving the pH-stability of versatile peroxidase by comparative structural analysis with a naturally-stable manganese peroxidase
PLoS ONE
10
e0140984
2015
Pleurotus eryngii (O94753), Pleurotus eryngii
Manually annotated by BRENDA team
Palma, C.; Lloret, L.; Sepulveda, L.; Contreras, E.
Production of versatile peroxidase from Pleurotus eryngii by solid-state fermentation using agricultural residues and evaluation of its catalytic properties
Prep. Biochem. Biotechnol.
46
200-207
2016
Pleurotus eryngii
Manually annotated by BRENDA team
Vignali, E.; Tonin, F.; Pollegioni, L.; Rosini, E.
Characterization and use of a bacterial lignin peroxidase with an improved manganese-oxidative activity
Appl. Microbiol. Biotechnol.
102
10579-10588
2018
Rhodococcus jostii (Q0SE24)
Manually annotated by BRENDA team
Gonzalez-Perez, D.; Alcalde, M.
The making of versatile peroxidase by directed evolution
Biocatal. Biotransform.
36
1-11
2018
Pleurotus eryngii (O94753)
-
Manually annotated by BRENDA team
Ravichandran, A.; Rao, R.G.; Thammaiah, V.; Gopinath, S.M.; Sridhar, M.
A versatile peroxidase from Lentinus squarrosulus towards enhanced delignification and in vitro digestibility of crop residues
BioResources
14
5132-5149
2019
Lentinus squarrosulus, Lentinus squarrosulus TAMI004
-
Manually annotated by BRENDA team
Ravichandran, A.; Rao, R.G.; Gopinath, S.M.; Sridhar, M.
Augmenting versatile peroxidase production from Lentinus squarrosulus and its role in enhancing ruminant feed
BioResources
16
1600-1615
2021
Lentinus squarrosulus, Lentinus squarrosulus 12292 ITS
-
Manually annotated by BRENDA team
Mannino, M.H.; Patel, R.S.; Eccardt, A.M.; Perez Magnelli, R.A.; Robinson, C.L.C.; Janowiak, B.E.; Warren, D.E.; Fisher, J.S.
Myoglobin as a versatile peroxidase implications for a more important role for vertebrate striated muscle in antioxidant defense
Comp. Biochem. Physiol. B
234
9-17
2019
Mus musculus (P04247), Equus caballus (P68082), Equus caballus
Manually annotated by BRENDA team
Sanchez-Alejandro, F.; Baratto, M.C.; Basosi, R.; Graeve, O.; Vazquez-Duhalt, R.
Addition of new catalytic sites on the surface of versatile peroxidase for enhancement of LRET catalysis
Enzyme Microb. Technol.
131
109429
2019
Bjerkandera adusta (Q3SC77), Bjerkandera adusta
Manually annotated by BRENDA team
Durdic, K.I.; Ostafe, R.; Durdevic Delmas, A.; Popovic, N.; Schillberg, S.; Fischer, R.; Prodanovic, R.
Saturation mutagenesis to improve the degradation of azo dyes by versatile peroxidase and application in form of VP-coated yeast cell walls
Enzyme Microb. Technol.
136
109509
2020
Pleurotus eryngii (Q9UVP6), Pleurotus eryngii
Manually annotated by BRENDA team
Liu, J.; Zhang, S.; Shi, Q.; Wang, L.; Kong, W.; Yu, H.; Ma, F.
Highly efficient oxidation of synthetic and natural lignin-related compounds by Physisporinus vitreus versatile peroxidase
Int. Biodeter. Biodegrad.
136
41-48
2019
Physisporinus vitreus, Physisporinus vitreus PF18
-
Manually annotated by BRENDA team
Zavarzina, A.G.; Lisov, A.V.; Leontievsky, A.A.
The role of ligninolytic enzymes laccase and a versatile peroxidase of the white-rot fungus Lentinus tigrinus in biotransformation of soil humic matter comparative in vivo study
J. Geophys. Res.
123
2727-2742
2018
Lentinus tigrinus, Lentinus tigrinus VKM F-160
-
Manually annotated by BRENDA team
Hernandez-Bueno, N.S.; Suarez-Rodríguez, R.; Balcazar-Lopez, E.; Folch-Mallol, J.L.; Ramirez-Trujillo, J.A.; Iturriaga, G.
A versatile peroxidase from the fungus Bjerkandera adusta confers abiotic stress tolerance in transgenic tobacco plants
Plants (Basel)
10
859
2021
Bjerkandera adusta (Q3SC77), Bjerkandera adusta, Bjerkandera adusta UAMH8258 (Q3SC77)
Manually annotated by BRENDA team