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1.11.1.13: manganese peroxidase

This is an abbreviated version!
For detailed information about manganese peroxidase, go to the full flat file.

Word Map on EC 1.11.1.13

Reaction

2 Mn(II) + 2 H+ +

H2O2
= 2 Mn(III) + 2 H2O

Synonyms

CmMnP, extralong PMnP, hybrid Mn-peroxidase, Il-MnP1, Il-MnP6, L-MnP, LeMnP2, long PMnP, manganese peroxidase, manganese peroxidase 2, manganese-dependent peroxidase, MGmn2, MGmnp1, MGmnp3, Mn-dependent (NADH-oxidizing) peroxidase, Mn2+: hydrogen peroxide oxidoreductase, Mn2+:H2O2 oxidoreductase, Mn2+:hydrogen peroxide oxidoreductase, MnP, MnP 1, MnP II, MnP-BBP6, MnP-GY, MnP-PGY, mnp1, MnP10, MnP117436, MnP12, MnP157986, MnP2, MnP3, MnP50297, MnP6, Moror_3885, MP, MrMnP1, multifunctional manganese peroxidase, Nf b19 MNP2, peroxidase, manganese, peroxidase-M2, rMnP3-BBP6, short manganese peroxidase, short MnP

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.13 manganese peroxidase

pH Range

pH Range on EC 1.11.1.13 - manganese peroxidase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2 - 6
-
active in the range, below pH 2 and above pH 6: completely inactive
3 - 3.5
-
pH 3.5: decrease of 95% of oxidation of Mn2+, pH 3: nearly no oxidation of Mn2+
3 - 5
-
oxidation of veratryl alcohol decreases more than 95% when the pH is increased from 3 to 4.5 and nearly absent at pH 5
3 - 8
3.1 - 6.1
-
veratryl alcohol oxidation, activity increases with increasing pH
3.1 - 8.3
-
in presence of H2O2 the formation of enzyme compound I is independent of pH over the range
3.5 - 4.5
-
optima for Mn2+-independent 2,6-dimethoxyphenol oxidation
3.5 - 5.5
over 50% of maximal activity within this range
3.5 - 6
3.5 - 6.5
-
Mn2+ oxidation shows an optimum in the range 5.5-5.75 and negligible activity at pH values below 3.5 and above 6.5
4 - 4.5
-
optima for Mn2+-dependent 2,6-dimethoxyphenol oxidation
4 - 5.5
-
about half-maximal activity at pH 4.0 and 5.5, 2,2-azino-bis-3-ethyl-6-benzothiazolinesulfonate-oxidation
4.5 - 5.7
-
about 65% of maximal activity at pH 4.5 and about 50% at pH 5.7, Mn(III)-lactate formation
5.5 - 5.8
-
the pH-activity profile for Mn2+ oxidation shows an optimum in the range 5.5 - 5.75 and negligible activity at pHs below 3.5 and above 6.5
additional information
-
MnP is active in a broad pH-range