1.11.1.10: chloride peroxidase

This is an abbreviated version!
For detailed information about chloride peroxidase, go to the full flat file.

Word Map on EC 1.11.1.10

1.11.1.10

fumago

caldariomyces

horseradish

chlorination

peroxidases

halogen

halide

haloperoxidase

bromination

lactoperoxidase

inaequalis

ferryl

curvularia

soret

bromoperoxidase

monochlorodimedone

low-spin

p450cam

vanadium-dependent

thioanisole

peroxidase-catalyzed

thiolate-ligated

pyrrocinia

oxoferryl

n,n-dimethylaniline

peroxygenases

agrocybe

vanadium-containing

hypohalous

aegerita

degradation

synthesis

environmental protection

biotechnology

Reaction

+ 2 H2O

Synonyms

CCPO, Chloride peroxidase, chloroperoxidase, chloroproxidase, CPO, CPO-I, CPO2, haeme-thiolate peroxidase, heme-containing CPO, heme-thiolate chloroperoxidase, More, peroxidase, chloride, Vanadium chloride peroxidase, vCPO

ECTree

1 Oxidoreductases

1.11 Acting on a peroxide as acceptor

1.11.1 Peroxidases

1.11.1.10 chloride peroxidase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
10	Activating Compound
2187	AA Sequence
11	Application
1	CAS Registry Number
5	Cloned(Commentary)
42	Cofactor
5	Crystallization (Commentary)
13	General Information
23	General Stability
15	Inhibitors
10	kcat/KM [mM/s]
41	KM Value [mM]
7	Localization
13	Metals/Ions
12	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
4	Organic Solvent Stability
107	Organism
1	Oxidation Stability
49	PDB ID
29	pH Optimum
9	pH Range
12	pH Stability
5	pI Value
12	Posttranslational Modification
6	Protein Variants
16	Purification (Commentary)
3	Reaction
8	Reaction Type
107	Reference
7	Source Tissue
6	Specific Activity [micromol/min/mg]
9	Storage Stability
286	Substrates and Products (Substrate)
6	Subunits
99	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
4	Temperature Range [°C]
27	Temperature Stability [°C]
35	Turnover Number [1/s]

Systematic Name

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Systematic Name on EC 1.11.1.10 - chloride peroxidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Systematic Name Search

chloride:hydrogen-peroxide oxidoreductase

Brings about the chlorination of a range of organic molecules, forming stable C-Cl bonds. Also oxidizes bromide and iodide. Enzymes of this type are either heme-thiolate proteins, or contain vanadate. A secreted enzyme produced by the ascomycetous fungus Caldariomyces fumago (Leptoxyphium fumago) is an example of the heme-thiolate type. It catalyses the production of hypochlorous acid by transferring one oxygen atom from H2O2 to chloride. At a separate site it catalyses the chlorination of activated aliphatic and aromatic substrates, via HClO and derived chlorine species. In the absence of halides, it shows peroxidase (e.g. phenol oxidation) and peroxygenase activities. The latter inserts oxygen from H2O2 into, for example, styrene (side chain epoxidation) and toluene (benzylic hydroxylation), however, these activities are less pronounced than its activity with halides. Has little activity with non-activated substrates such as aromatic rings, ethers or saturated alkanes. The chlorinating peroxidase produced by ascomycetous fungi (e.g. Curvularia inaequalis) is an example of a vanadium chloroperoxidase, and is related to bromide peroxidase (EC 1.11.1.18). It contains vanadate and oxidizes chloride, bromide and iodide into hypohalous acids. In the absence of halides, it peroxygenates organic sulfides and oxidizes ABTS [2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid)] but no phenols.