1.10.3.15: grixazone synthase

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For detailed information about grixazone synthase, go to the full flat file.

Reaction

2 3-amino-4-hydroxybenzoate +

Synonyms

GriF

ECTree

     1 Oxidoreductases

         1.10 Acting on diphenols and related substances as donors

             1.10.3 With oxygen as acceptor

                1.10.3.15 grixazone synthase

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Results	in table
1	Activating Compound
4	AA Sequence
1	Cloned(Commentary)
2	General Information
15	Inhibitors
8	kcat/KM [mM/s]
7	Ki Value [mM]
6	KM Value [mM]
3	Metals/Ions
1	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
13	Organism
6	Pathway
2	pH Optimum
1	pH Range
1	pH Stability
1	Purification (Commentary)
1	Reaction
5	Reference
2	Specific Activity [micromol/min/mg]
18	Substrates and Products (Substrate)
2	Subunits
4	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
6	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 1.10.3.15 - grixazone synthase

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SYSTEMATIC NAME

IUBMB Comments

3-amino-4-hydroxybenzoate:N-acetyl-L-cysteine:oxygen oxidoreductase

A type 3 multi copper protein. The enzyme, isolated from the bacterium Streptomyces griseus, catalyses an 8 electron oxidation. Activation of the enzyme requires a copper chaperone (GriE). It also acts on 3-amino-4-hydroxybenzaldehyde, giving grixazone A. The second aldehyde group is presumably lost as formate. The enzyme also catalyses the reaction of EC 1.10.3.4 o-aminophenol oxidase.