1.1.99.40: (R)-2-hydroxyglutarate-pyruvate transhydrogenase

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For detailed information about (R)-2-hydroxyglutarate-pyruvate transhydrogenase, go to the full flat file.

Reaction

Synonyms

D-2-hydroxyglutarate-pyruvate transhydrogenase, DLD3

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.99 With unknown physiological acceptors

                1.1.99.40 (R)-2-hydroxyglutarate-pyruvate transhydrogenase

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Results	in table
3	AA Sequence
1	Cofactor
1	General Information
2	kcat/KM [mM/s]
2	KM Value [mM]
1	Localization
2	Metals/Ions
1	Organism
2	Pathway
1	Purification (Commentary)
1	Reaction
1	Reference
4	Substrates and Products (Substrate)
3	Synonyms
1	Systematic Name
2	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 1.1.99.40 - (R)-2-hydroxyglutarate-pyruvate transhydrogenase

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SYSTEMATIC NAME

IUBMB Comments

(R)-2-hydroxyglutarate:pyruvate oxidoreductase [(R)-lactate-forming]

The enzyme, characterized in the yeast Saccharomyces cerevisiae, also functions as EC 1.1.2.4, D-lactate dehydrogenase (cytochrome), and is active with oxaloacetate as electron acceptor forming (R)-malate.