1.1.99.21: D-sorbitol dehydrogenase (acceptor)
This is an abbreviated version!
For detailed information about D-sorbitol dehydrogenase (acceptor), go to the full flat file.
Reaction
Synonyms
D-sorbitol dehydrogenase, FAD-SLDH, GoSLDH, mSLDH, PQQ-dependent D-sorbitol dehydrogenase, SDH, SLDH, sldhAB, sorbitol dehydrogenase
ECTree
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Cofactor
Cofactor on EC 1.1.99.21 - D-sorbitol dehydrogenase (acceptor)
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2,6-dichlorophenolindophenol
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acts in vitro as acceptor together with phenazine methosulfate
pyrroloquinoline quinone
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the cofactor transfers redox equivalents to the respiratory chain during the biotransformation of NHEG to 6NSL
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tightly bound , dehydrogenase-cytochrome c complex, separable by SDS-PAGE
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NAD+, NADP+ or molecular oxygen are completely inactive
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additional information
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NAD+, NADP+ or molecular oxygen are completely inactive
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additional information
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enzyme GoSLDH exhibits a preference for NADP+ over NAD+ as a coenzyme and is exclusively an NADP+-dependent enzyme showing only 2.5% relative activity with NAD+
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