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1.1.99.14: glycolate dehydrogenase

This is an abbreviated version!
For detailed information about glycolate dehydrogenase, go to the full flat file.

Word Map on EC 1.1.99.14

Reaction

glycolate
+
acceptor
=
glyoxylate
 +
reduced acceptor

Synonyms

GADH, GDH, GlcD, GlcD1, GlcD2, GlcDH, glycolate dehydrogenase, glycolate dehydrogenase I, glycolate oxidoreductase, glycolic acid dehydrogenase, More

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.14 glycolate dehydrogenase

Inhibitors

Inhibitors on EC 1.1.99.14 - glycolate dehydrogenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
8-oxyquinoline
-
80% residual activity at 1 mM
Aminooxyacetate
-
competitive to glycolate and glyoxylate
Co2+
-
88% residual activity at 1 mM
crude oil
-
33-54% inhibition at 1-2 ml l-1, complete inhibition at 4 ml l-1
-
Cu2+
-
complete inhibition at 1 mM
CuSO4
cyanide
-
-
Cyclohexane
-
33-68% inhibition at 0.01-0.03% (v/v), complete inhibition at 0.04% (v/v)
cytochrome c
-
inhibits rate of phenazine methosulfate stimulated dichlorophenolindophenol reduction
DW 1750000
-
91% residual activity at 1 mM
EDTA
-
8% inhibition at 10 mM
Fe3+
-
73% residual activity at 1 mM
glyoxylate
Hg2+
-
2% residual activity at 1 mM
HgCl2
-
complete
hydrazine
-
77% residual activity at 1 mM
hydroxylamine
-
83% residual activity at 1 mM
iodoacetic acid
-
63% residual activity at 1 mM
K3[Fe(CN)6]
-
complete inhibition
Mn2+
-
complete inhibition at 1 mM
N-ethylmaleimide
-
56% residual activity at 1 mM
Ni2+
-
complete inhibition at 1 mM
o-phenanthroline
-
88% residual activity at 1 mM
Sodium azide
-
85% residual activity at 1 mM
Zn2+
-
76% residual activity at 1 mM
additional information
-