1.1.99.1: choline dehydrogenase

This is an abbreviated version!
For detailed information about choline dehydrogenase, go to the full flat file.

Word Map on EC 1.1.99.1

1.1.99.1

betaine

badhs

pcyt1a

mthfd1

dimethylglycine

glycine-betaine

betaine-aldehyde

medicine

diagnostics

Reaction

Synonyms

Cdh, CHD, CHDH, ChoDH, choline dehydrogenase, choline oxidase, choline-cytochrome c reductase, choline:(acceptor) oxidoreductase, dehydrogenase, choline, oxidase, choline

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.99 With unknown physiological acceptors

1.1.99.1 choline dehydrogenase

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Results	in table
3	Activating Compound
12267	AA Sequence
3	Application
1	CAS Registry Number
9	Cloned(Commentary)
12	Cofactor
53	Disease/ Diagnostics
1	Expression
18	General Information
6	General Stability
28	Inhibitors
2	Ki Value [mM]
11	KM Value [mM]
18	Localization
1	Metals/Ions
6	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
33	Organism
6	Pathway
6	pH Optimum
2	pH Range
2	pH Stability
1	pI Value
1	Posttranslational Modification
3	Protein Variants
8	Purification (Commentary)
3	Reaction
3	Reaction Type
29	Reference
31	Source Tissue
7	Specific Activity [micromol/min/mg]
7	Storage Stability
66	Substrates and Products (Substrate)
9	Subunits
21	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
5	Temperature Stability [°C]

Natural Substrates Products

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Natural Substrates Products on EC 1.1.99.1 - choline dehydrogenase

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choline + 2 acceptor + H2O

glycine-betaine + 2 reduced acceptor + H+

Halomonas elongata

four electron oxidation with betaine aldehyde as intermediate, provides glycine-betaine as compatible solute

654268

choline + acceptor

betaine aldehyde + reduced acceptor

7 entries

choline + coenzyme Q1

betaine aldehyde + reduced coenzyme Q1

Rattus norvegicus

mitochondrial oxidation of choline

389886

additional information

Rattus norvegicus

the enzyme is responsible for the two-step choline oxidation to betaine together with the betaine-homocysteine methyltransferase

675565